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Table 5 Characteristics of preferred clinical trials*

From: Factors influencing the participation of gastroenterologists and hepatologists in clinical research

Characteristic

Specialty

Experience

 

Gastroenterology (n = 160)

Hepatology (n = 189)

Less Experienced Researchers (n = 159)

More Experienced Researchers (n = 62)

Phase 1 trials

36 (22.5)†

73 (38.6)†

59 (37.1)†

32 (51.6)†

Phase 2 trials

64 (40.0)†

107 (56.6)†

91 (57.2)†

52 (83.9)†

Phase 3 trials

97 (60.6)

108 (57.1)

114 (71.7)†

53 (85.5)†

Phase 4 trials

76 (47.5)†

68 (36.0)†

92 (57.9)

28 (45.2)

Duration ≤ 2 years

100 (62.5)

126 (66.7)

127 (79.9)†

58 (93.6)†

Duration > 2 years

38 (23.8)

59 (31.2)

57 (35.9)†

35 (56.5)†

Trials with placebo or no treatment arm

51 (31.9)

55 (29.1)

68 (42.8)

28 (45.2)

Trials involving invasive procedures

40 (25.0)†

30 (15.9)†

44 (27.7)

18 (29.0)

Multiple-arm and crossover protocols

36 (22.5)

35 (18.5)

40 (25.2)†

24 (38.7)

Industry funding

76 (47.5)

104 (55.0)

86 (54.1)†

50 (80.7)†

Government funding

78 (48.8)†

121 (64.0)†

104 (65.4)†

56 (90.3)†

Non-government funding

78 (48.8)

103 (54.5)

96 (60.4)†

51 (82.3)†

  1. * Values are expressed as number (percentage) responding "very interested".
  2. † P ≤ .05 for the comparison between specialties or between clinical and non-clinical researchers.