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Table 1 Model parameter descriptions and values

From: Cost effectiveness of chest pain unit care in the NHS

Parameter Description Source Distributions
    Beta Distribution
    Mean Alpha (Beta)
pSTEMI Probability of chest pain patients with ST-elevation myocardial infarction Trial data: audited patients with ST-elevation myocardial infarction/all patients with chest pain 0.036 4800 (130000)
pACSdisc Probability of being discharged with ACS at a hospital with no CPU External data [8] 0.012 7.55 (621.82)
Incmort Probability of inadvertent discharge upon ACS mortality, compared to admission External data [9] 0.03 10.92 (353.1)
    Normal Distribution
    Mean Standard Error
mortSTEMI Mortality of ST-elevation myocardial infarction at hospitals with no CPU Modelled from trial onset to needle time data using Boersma equation [7] 0.1003 0.0004
CPUdisc Effect of CPU availability upon probability of being discharged with ACS Trial data: effect of CPU upon (re)admission of initially discharged chest pain patients 1.256 0.1962
cpu_STEMI CPU availability impact upon mortality from ST-elevation myocardial infarction Modelled from trial onset to needle time data using Boersma equation 0.0007 0.0013
routQALY QALYs accrued up to six months after initial attendance at a hospital with no CPU Trial data: Area under the curve for health utility for all patients attending a hospital with no active CPU 0.318 0.0038
cpuQALY Effect of CPU availability upon QALYs accrued up to six months after initial attendance Trial data: Effect of CPU availability upon area under the curve for health utility 0.0084 0.0129
ltQALY Lifetime QALYs accrued by a typical patient with coronary heart disease External data: Vergel et al [6] 6.829 0.3401
routCOST Costs up to six months after initial attendance at a hospital with no CPU Trial data: Mean cost per patient for all attending a hospital with no CPU 2405 63.5216
cpuCOST Effect of CPU availability upon costs up to six months after initial attendance Trial data: Effect of CPU availability upon mean cost per patient -31 219.647
ltCOST Lifetime costs of care for a typical patient with coronary heart disease External data: Vergel et al [6] 10,079 2200