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Table 2 Questions used to assess scientific quality of the study and the reader's ability to adequately understand the intervention

From: Too little but not too late: Results of a literature review to improve routine immunization programs in developing countries

Questions

Trials with Comparison Groups

Trials with evaluation before & after

Observational

Is the strategy defined?

Yes

Yes

Yes

Is there a methods section?

Yes

Yes

Yes

Are the strategy and methods sections defined in a comprehensive way?

Yes

Yes

Yes

Is the study question clearly defined?

Yes

Yes

No

Are outcomes/outputs clearly defined?

Yes

Yes

No

Can outcomes be attributed to interventions?

Yes

Yes

No

Is the explanation of the target population sufficient?

Yes

Yes

Yes

Is the target population studied appropriate?

Yes

Yes

No

Was the method used to obtain cases and controls explained?

Yes

No

No

Was randomization used to select cases and controls?

Yes

No

No

Was the method of selecting cases and controls appropriate?

Yes

No

No

Was a method for checking immunization status described?

Yes

Yes

Yes

Was the method for determining sample size provided?

Yes

Yes

No

Have confounders been identified?

Yes

Yes

No

Were the confounders taken into consideration?

Yes

Yes

No

Was the time frame of the study defined?

Yes

Yes

No

Is the time frame sufficient for the intervention to have an impact?

Yes

Yes

Yes

Did the authors make comments regarding limitations of the strategy?

Yes

Yes

Yes

Did the authors compare results with similar studies?

Yes

Yes

Yes

Was adequate data analysis conducted?

Yes

Yes

Yes

Was the response rate adequate?

No

Yes

No