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Table 1 Liver function tests and definitions of abnormal

From: Development of a decision support tool to facilitate primary care management of patients with abnormal liver function tests without clinically apparent liver disease [HTA03/38/02]. Abnormal Liver Function Investigations Evaluation (ALFIE)

Liver Function test

Range

Normal (Age & Gender)

Moderately abnormal

Severely abnormal

Bilirubin (μmol/l)

0–1000

<18 M

<16 F

18 – 42.5 M

16 – 37.5 F

>42.5 M

>37.5 F

Albumin (g/l)

11–60

>35

30–35

<30

Alk Phos (IU/l)

20–2000

120–455 M 16–19

455–1138

>1138

  

45 – 195 M 19–26

195–488

>488

  

30 – 105 M 26–55

105–263

>263

  

45 – 130 M 56–75

130–325

>325

  

65 – 150 M 75+

150–375

>375

  

120–420 F 16–19

420–1050

>1050

  

25 – 90 F 19–26

90–225

>225

  

20 – 80 F 26–55

80–200

>200

  

40 – 150 F 56–75

150–375

>375

  

50 – 190 F 75+

190–475

>475

GGT (IU/l)

5–2000

7 – 42 All 16–24

42–105

>105

  

9 – 70 M 24–34

70–175

>175

  

11– 75 M 34–44

75–188

>188

  

11 – 82 M 44–55

82–205

>205

  

11 – 70 M 55+

70–175

>175

  

5 – 35 F 24–34

35–88

>88

  

5 – 42 F 34–44

42–105

>105

  

5 – 65 F 44–55

65–163

>163

  

5 – 75 F 55+

75–188

>188

ALT (IU/l)

12–9999 depending on age and sex

14 – 40 M 16–18

40–100

>100

  

15 – 55 M 18–55

55–138

>138

  

12 – 35 F 16–18

35–88

>88

  

12 – 40 F 18–55

40–100

>100

  

13 – 43 All 55–75

43–108

>108

  

6 – 30 All 75+

30–75

>75

AST (IU/l)

 

3 – 30 M 17–65

30 – 75

>75

  

10 – 45 F 16–75

45 – 113

>113

  

10 – 30 75+

30 – 75

>75