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Table 1 Nonadherence in antidepressant use: results of the binomial multilevel analyses on early dropouts and continuers and on refill nonadherence

From: Patient risk profiles and practice variation in nonadherence to antidepressants, antihypertensives and oral hypoglycemics

  Early dropout (0 = continuer; 1 = early dropout) Refill adherence (0 = adherent > 80%; 1 = nonadherent)
  Oddsratioa) 95% CI Oddsratioa) 95% CI
Socio-demographic characteristics     
-age (mean; SD) 1.00 [0.99–1.01] 1.00 [1.00–1.00]
-% woman 0.78* [0.63–0.95] 1.00 [0.84–1.19]
-% college/university 1.05 [0.80–1.36] 0.86 [0.69–1.09]
-% non-western 2.47* [1.70–3.60] 2.59* [1.75–3.82]
-% private insurance 1.06 [0.85–1.33] 0.95 [0.78–1.15]
-% living together 1.02 [0.80–1.29] 1.00 [0.82–1.21]
-% with job/study 1.26 [1.00–1.60] 0.88 [0.73–1.07]
Use of medication     
Antidepressants     
- % users of SSRIs 0.80 [0.59–1.08] 1.27* [1.04–1.63]
- % users of TCAs 1.55* [1.14–2.11] 0.76* [0.58–0.99]
- % users of other antidepressants reference   reference  
Complex regime     
number of other ATCs (mean;sd) 1.02 [1.00–1.05] 0.97* [0.95–0.99]
Health & morbidity in general practice     
Self-reported health     
% excellent/good 1.20 [0.98–1.47] 1.17 [0.99–1.37]
Diagnoses for which GP is consulted (% of patients)     
Depression (P03/P76) 0.62* [0.50–0.76] 0.91 [0.77–1.07]
Anxiety (P01/P74) 0.75* [0.57–0.98] 1.15 [0.93–1.42]
Neurasthenia (P78) 2.01* [1.34–3.04] 0.82 [0.51–1.31]
Other diagnoses in P-chapter (P01–P99) 1.18 [0.95–1.47] 1.17 [0.97–1.41]
GP consultation for chronic diseases and overall contact     
Number of other chronic complaints (mean, SD) 1.14* [1.05–1.24] 1.18* [1.09–1.27]
Number of contacts with GP (mean; SD) 0.99 [0.98–1.00] 0.99 [0.98–1.00]
Number of patients (N) 4,877 3,777
  1. * P < 0.05
  2. a) odds ratio > 1: more likely to be an early dropout; odds ratio < 1: less likely to be an early dropout