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Table 5 Sensitivity Analyses: Base case and upper and lower bound assumptions for the input variables*

From: Effect of a restrictive transfusion strategy on transfusion-attributable severe acute complications and costs in the US ICUs: a model simulation

Input variable Base case assumption Lower bound Upper bound
% Adult ICU patients at risk for a late TF 29%a 13%b 50%c
Number of pRBC units/1 TSAC 33d 19d 552d
Cost per 1u pRBC $634e $250f $800f
  1. *pRBC, packed red blood cells; TF, transfused; TSAC, transfusion-attributable severe acute complication
  2. aBased on % patients of the total pool screened deemed eligible for enrollment into Corwin study16
  3. bBased on % patients of the total pool screened for the TRICC trial who gave their consent15
  4. cBased on % patients of the total pool screened for the TRICC trial deemed eligible for enrollment15
  5. dBased on 95% CI for the combine CV and ARDS complications from Hebert15
  6. eBased on Cremieux21
  7. fBased on anecdotal reports (see text for rationale)