Effect of a restrictive transfusion strategy on transfusion-attributable severe acute complications and costs in the US ICUs: a model simulation

Table 5 Sensitivity Analyses: Base case and upper and lower bound assumptions for the input variables*

Input variable	Base case assumption	Lower bound	Upper bound
% Adult ICU patients at risk for a late TF	29%^a	13%^b	50%^c
Number of pRBC units/1 TSAC	33^d	19^d	552^d
Cost per 1u pRBC	$634^e	$250^f	$800^f

*pRBC, packed red blood cells; TF, transfused; TSAC, transfusion-attributable severe acute complication
^aBased on % patients of the total pool screened deemed eligible for enrollment into Corwin study¹⁶
^bBased on % patients of the total pool screened for the TRICC trial who gave their consent¹⁵
^cBased on % patients of the total pool screened for the TRICC trial deemed eligible for enrollment¹⁵
^dBased on 95% CI for the combine CV and ARDS complications from Hebert¹⁵
^eBased on Cremieux²¹
^fBased on anecdotal reports (see text for rationale)

ISSN: 1472-6963