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Table 3 Transfusion-attributable severe acute complications and units packed red blood cells/1 transfusion-attributable severe acute complications derivation*

From: Effect of a restrictive transfusion strategy on transfusion-attributable severe acute complications and costs in the US ICUs: a model simulation

Population variable Input Source Output
CV SAC    
   Liberal 88 (21.0%) Hebert 1999 [15]  
   Restrictive 55 (13.2%) Hebert 1999 [15]  
   CV TSAC 88-55 Hebert 1999 [15] 33 (7.8%, 95% CI 2.7–12.9%)
ARDS SAC    
   Liberal 48 (11.4%) Hebert 1999 [15]  
   Restrictive 32 (7.7%) Hebert 1999 [15]  
   ARDS TSAC 48-32 Hebert 1999 [15] 16 (3.8%, 95% CI–0.2–7.8%)
CV+ARDS TSAC 33+16   49
Total pRBC units TF liberal 5.6 u/pt x 420 pts TF Hebert 1999 [15] 2,352
Total pRBC TF restrictive 2.6 u/pt x (418 x 0.67) pts TF Hebert 1999 [15] 728
pRBC units TF excess 2,352–728   1,624
pRBC units/1 TSAC 1,624/49   33
  1. * CV SAC, cardiovascular severe acute complication; CV TSAC, cardiovascular transfusion-attributable severe acute complication; ARDS SAC, adult respiratory distress syndrome severe acute complication; ARDS TSAC, adult respiratory distress syndrome transfusion-attributable severe acute complication