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Table 2 Outcome measures in study of the effect of a pedagogic intervention towards groups of Norwegian GPs, concerning inappropriate prescription patterns in elderly patients ≥ 70 years

From: A cluster-randomized educational intervention to reduce inappropriate prescription patterns for elderly patients in general practice – The Prescription Peer Academic Detailing (Rx-PAD) study [NCT00281450]

Baseline prescription patterns collected during one year:
   • Proportion of inappropriate prescriptions for elderly patients ≥ 70 years
Change (%) in prescription patterns compared to baseline in elderly patients ≥ 70 years, regarding the following drugs and combination of drugs, one year after the initiation of a tailored pedagogic intervention:
   • Tricyclic antidepressants (Amitriptyline, Doxepin, Trimipramine)
   • 1st generation antihistamines (Dexchlorphenamine, Promethazine, Alimemazine, Hydroxycin)
   • 1st generation low potency antipsychotics (Clorpromazine, Chlorprotixene, Levoprometazine, Prochlorperazine)
   • Long acting benzodiazepines (Nitrazepam, Flunitrazepam)
   • The muscle relaxant Carisoprodol
   • Strong analgesics poorly tolerated by the elderly (Propoxyphene, Pethidine, opioids with spasmolytics)
   • Theophylline per os
   • Beta blocking agents combined with unselective calcium channel blockers (Verapamil, Diltiazem)
   • NSAIDs combined with Warfarin
   • NSAIDs or Cox2-inhibitor combined with ACE-inhibitor or A2-blocker
   • NSAIDs combined with SSRI
   • The difference in "total prescription change score" between the intervention group and the control group
Prescription logistic issues:
   • Agreement between drugs listed as "regular" in the physicians' electronic medical record (EPR) systems and dispensed drugs, registered in the Norwegian Prescription Database (NorPD)
   • Agreement between prescribed and dispensed drugs, registered in the Norwegian Prescription Database (NorPD)
Methodological issues:
   • Development of rational prescription patterns and related quality indicators (QIs) for elderly out-patients ≥ 70 years
   • Feasibility evaluation of a large cluster randomized educational intervention study in general practice settings