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Table 2 Data from eight peer-reviewed studies describing the effect of the TWR on their colorectal services.

From: The effects of the Two-Week Rule on NHS colorectal cancer diagnostic services: A systematic literature review

First author
& Reference
N° TWR
referrals received
(i) % of CRCs identified
from TWR referrals (n)
Total number of CRC
cases diagnosed †
Total % of CRC cases
referred as...
     TWR Emergency Other
Chohan [6] 462 13.8% (64) 195 32.8% 20% 47.2%
Maruthachalam [7] 639 8% (51) 234 21.8% 10.6% 67.6%
Eccersley [8] 180 14.4% (26) 145 18% 17% 66%
Walsh [9] 78 10.3% (8) 23 47.8% 52.2%
Debnath [10] 237 8.9% (21) 96 21.9% 78.1%
Flashman [11] 695 9.4% (65) 249 26.1% 35.3% 38.6%
Barwick [12] 149 10% (14) 84 16.7% 41.7% 41.7%
Tricket [13] NA NA 147 20% 29% 51%
Weighted averages of all values combined 10.3%   24% 24.1% 52.4%
  1. Key: NA = Data not available in article; † = Total number of CRC cases diagnosed during the time of the study in the same locality.