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Table 1 POWER CALCULATION GRID

From: CESAR: conventional ventilatory support vs extracorporeal membrane oxygenation for severe adult respiratory failure

  

Mortality in Control Group

  

70%

  

60%

  

50%

  

45%

  

% of survivors severely disabled

15%

10%

5%

15%

10%

5%

15%

10%

5%

15%

10%

5%

 

Primary adverse outcome %

74.5

73

71.5

66

64

62

57.5

55

52.5

53.25

50.5

47.75

Relative risk

0.5

64

66

70

82

86

92

104

112

122

118

128

140

 

0.67

136

142

150

180

192

204

236

256

278

270

296

326

 

0.75

224

236

250

302

324

348

404

440

480

468

514

566

 

0.8

336

356

378

462

496

532

624

682

746

726

800

62

  1. Sample size calculation for different assumptions about mortality, disability and relative risk (Beta = 0.2, Alpha = 0.05, 2 sided)