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Table 5 Hazard ratios for thirteen-year all cause mortality by number of symptoms in five symptom categories

From: Symptom experience and subsequent mortality: results from the West of Scotland Twenty-07 study

   n in sample* Died n (%) Unadjusted Hazard Ratio (95% CI) Hazard ratio (95% CI) adjusted for socio-demographic factors1 Hazard ratio (95% CI) adjusted for socio-demographic factors and chronic conditions2 Hazard ratio (95% CI) adjusted for socio-demographic factors, chronic conditions and self-assessed health3
Number of symptoms in the last month 0 87 9 (10.3) 1.00 1.00 1.00 1.00
  1 116 16 (13.8) 1.32 (0.58 to 2.99) 1.40 (0.62 to 3.17) 1.21 (0.53 to 2.75) 1.24 (0.54 to 2.82)
  2 128 27 (21.1) 2.13 (1.00 to 4.54) 2.06 (0.96 to 4.41) 1.94 (0.90 to 4.15) 1.99 (0.93 to 4.29)
  3–5 309 60 (19.4) 1.99 (0.99 to 4.00) 1.99 (0.98 to 4.03) 1.74 (0.85 to 3.55) 1.40 (0.68 to 2.86)
  ≥ 6 218 58 (26.6) 2.76 (1.37 to 5.58) 2.53 (1.24 to 5.16) 2.03 (0.99 to 4.19) 1.38 (0.65 to 2.89)
Number of symptoms in the last month which participants tended to have 0 120 15 (12.5) 1.00 1.00 1.00 1.00
  1 141 18 (12.8) 0.99 (0.50 to 1.97) 1.06 (0.53 to 2.10) 1.00 (0.50 to 1.99) 0.99 (0.50 to 1.97)
  2 138 28 (20.3) 1.68 (0.90 to 3.15) 1.66 (0.88 to 3.13) 1.62 (0.86 to 3.05) 1.51 (0.80 to 2.86)
  3–5 291 59 (20.3) 1.70 (0.96 to 2.99) 1.60 (0.90 to 2.80) 1.44 (0.81 to 2.56) 1.14 (0.64 to 2.06)
  ≥ 6 168 50 (29.8) 2.56 (1.44 to 4.57) 2.23 (1.24 to 4.02) 1.85 (1.01 to 3.37) 1.15 (0.61 to 2.18)
Number of symptoms in the last month which participants did not tend to have 0 588 123 (20.9) 1.00 1.00 1.00 1.00
  1 156 29 (18.6) 0.85 (0.57 to 1.28) 0.90 (0.60 to 1.36) 0.93 (0.61 to 1.40) 0.98 (0.65 to 1.49)
  2 59 11 (18.6) 0.89 (0.48 to 1.64) 1.18 (0.63 to 2.20) 1.20 (0.64 to 2.25) 1.16 (0.62 to 2.18)
  ≥ 3 55 7 (12.7) 0.61 (0.28 to 1.30) 0.71 (0.33 to 1.53) 0.67 (0.31 to 1.44) 0.72 (0.33 to 1.55)
Number of symptoms in the last month which resulted in cutting down on usual activities 0 526 84 (16.0) 1.00 1.00 1.00 1.00
  1 130 30 (23.1) 1.50 (0.99 to 2.28) 1.45 (0.95 to 2.21) 1.40 (0.92 to 2.14) 1.19 (0.77 to 1.82)
  2 66 18 (27.3) 1.74 (1.03 to 2.93) 1.54 (0.90 to 2.61) 1.41 (0.82 to 2.41) 1.05 (0.60 to 1.83)
  3–5 97 22 (22.7) 1.54 (0.96 to 2.46) 1.35 (0.84 to 2.18) 1.17 (0.72 to 1.90) 0.85 (0.51 to 1.40)
  ≥ 6 39 16 (41.0) 3.21 (1.88 to 5.49) 2.42 (1.39 to 4.20) 1.72 (0.97 to 3.06) 1.21 (0.67 to 2.21)
Number of symptoms in the last month which resulted in consulting the GP 0 457 72 (15.8) 1.00 1.00 1.00 1.00
  1 166 39 (23.5) 1.55 (1.05 to 2.29) 1.49 (1.00 to 2.21) 1.48 (0.99 to 2.20) 1.38 (0.93 to 2.06)
  2 91 19 (20.9) 1.39 (0.84 to 2.31) 1.46 (0.88 to 2.43) 1.36 (0.82 to 2.27) 1.13 (0.67 to 1.91)
  3–5 96 24 (25.0) 1.63 (1.02 to 2.61) 1.51 (0.94 to 2.43) 1.34 (0.83 to 2.16) 1.08 (0.66 to 1.75)
  ≥ 6 48 16 (33.3) 2.51 (1.46 to 4.31) 1.96 (1.13 to 3.41) 1.58 (0.91 to 2.77) 1.13 (0.63 to 2.01)
  1. * Numbers in each of the five symptom categories add to 858 the total number in the cohort. Numbers given are relevant for unadjusted hazard ratios. Numbers in the sample for each of the adjusted analyses varies only slightly since there was little missing data for the factors we have adjusted for (as can be seen from tables 1 and 2).
  2. 1 Adjusted for gender, housing tenure and smoking status
  3. 2 Adjusted for gender, housing tenure, smoking status and the presence of a respiratory or cardiovascular condition
  4. 3 Adjusted for gender, housing tenure, smoking status, the presence of a respiratory or cardiovascular condition and self-assessed health