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Table 2 Mean total number of drug prescriptions per GP per year, standardised per 1000 enlisted patients for the randomised more intensively involved group in the intervention region versus a matched control group

From: Does a joint development and dissemination of multidisciplinary guidelines improve prescribing behaviour: a pre/post study with concurrent control group and a randomised trial

 

Desired direction of drug

pre

Short term

Δ short term

Long term

Δ Long term

  

I (n = 27)

C (n = 26)

I (n = 27)

C (n = 23)

I (n = 27)

C (n = 26)

I (n = 27)

C (n = 26)

I (n = 27)

C (n = 26)

Drug indicators

           

Antibiotics2

↓

611 (536,833)

530 (421,665)

643 (413,812)

524 (443,622)

6 (-43,82)

3 (-48,38)

661 (435–734)

526 (418,649)

11 (-92,73)

-7 (-61,47)

Chinolones2

↓↓

34 (18,51)

25 (14,36)

27 (12,47)

24 (12,32)

3 (-12,8)

-2 (-8,2)

30 (21,38)

19 (17,33)

-3 (-11,3)

-1 (-7,5)

Nitrofurantoin1

↑

23 (15,31)

31 (21,40)

27 (20,35)

31 (21,42)

4 (-3,12)

1 (-3,5)

32 (24,41)

36 (26,46)

9 (1,18)

6 (0,11)

Trimethoprim1

↑

32 (22,41)

29 (19,38)

32 (20,44)

28 (20,37)

1 (-6,7)

0 (-4,3)

26 (18,35)

23 (16,31)

-5 (-13,3)

-5 (-11,0)

Amoxicillin with clav.acid2

↓

33 (22,68)

28 (16,43)

41 (16,67)

26 (17,45)

5 (-9,19)

-2 (-8,5)

23 (16,64)

30 (21,37)

-3 (-16,10)

3 (-8,10)

Amoxicillin1

↓

92 (59,125)

104 (63,145)

57 (37,76)

98 (62,135)

-36 (-75,4)

-5 (-16,6)

78 (37,119)

96 (65,128)

-14 (-36,8)

-7 (-25,10)

Doxycyclin1

↓

125 (89,160)

89 (73,105)

113 (82,144)

86 (71,100)

-12 (-37,14)

-4 (-12,5)

103 (74,132)

81 (69,93)

-22 (-52,8)

-8 (-16,0)

Mupirocin1

↓

12 (5,20)

7 (4,9)

10 (3,16)

6 (3,9)

-3 (-5,0)

-1 (-3,2)

8 (4,12)

6 (3,8)

-5 (-9,0)

-1 (-3,1)

Cholesterol synthesis inhibitors (Statins) 1

↑↑

150 (119,182)

139 (109,170)

182 (144,220)

166 (129,203)

32 (20,43)

27 (17,36)

229 (185,273)

194 (153,235)

79 (60,98)

55 (35,75)

Asthma & COPD

           

Long-term beta2-sympaticomimetics1

↑

35 (27,44)

36 (28,43)

34 (25,42)

33 (25,41)

-2 (-5,2)

-2 (-7,2)

32 (23,42)

28 (21,35)

-3 (-8,3)

-8 (-14, -2)

Asthma

           

Short-term beta2-sympaticomimetics1

↓

37 (26,48)

35 (23,47)

37 (26,48)

37 (25,49)

0 (-4,4)

2 (-1,6)

34 (24,44)

36 (24,48)

-3 (-8,2)

1 (-4,6)

Inhaled corticosteroids2

↑

24 (16,35)

24 (13,28)

22 (12,32)

21 (12,33)

-5 (-8,0)

-1 (-5,5)

15 (10,29)

19 (13,28)

-9 (-11, -4)

1 (-7,1)*

COPD

           

Short-term beta2-sympaticomimetics1

-

65 (51,79)

38 (29,47)

63 (48,79)

39 (29,48)

-2 (-9,6)

1 (-4,5)

61 (45,77)

32 (25,40)

-4 (-12,5)

-5 (-12,1)

Inhaled corticosteroids1

↓

59 (45,74)

48 (37,59)

55 (40,70)

46 (34,60)

-5 (-10,1)

-2 (-7,3)

41 (29,53)

39 (28,50)

-18 (-26, -11)

-9 (-16, -2)

  1. 1. Mean (CI) for normally distributed variables
  2. 2 Median (P25-P75 intervals) for skewed variables
  3. * T-test unpaired/Mann-Whitney p < 0.01