Table 1 Data input for the model
Estimated parameter | Setting | Baseline estimate | Range for sensitivity analysis | Extremes | Source |
|---|---|---|---|---|---|
Prevalence of newborn hearing impairment % | H C | 0.15 | 0.09–0.3 | 0.01–0.2 0.01–0.2 | Literature [3][4][14][15][16] |
Sensitivity of screening % | H C | 96 | 96–100 | 70–99 70–99 | Literature [10] |
Specificity of screening % | H C | 99 | 99 | 70–99 | data from sites, calculated |
Coverage of screening % | H C | 97 | 97 | 50–99 | data from sites |
Follow-up after screening % | H C | 95 | 95 | Authors' estimate | |
Healthy children under suspicion of hearing impairment % | H C | 0.1 | 0.1 | Authors' estimate | |
Discounting factor Costs % | H C | 6 per year 6 per year | |||
Effects % | H C | 1.5 per year 1.5 per year | |||
Probability of "natural" discovery without systematic screening | H C | Distribution, smoothed Weibull curve | Median age at diagnosis 18 months | Empirical data [18] | |
Costs of screening per child | H C | £ 35.58 (32–40) | £ 31.99 (29–35) | £ 28–59 £ 27–43 | Data from sites |
Costs of audiological follow-up of referrals | H C | £ 160 | £ 160 | Estimate from sites |