|
Depression severity
|
6/17
|
10/17
|
-
|
-
|
Moderate
| |
|
Transient side effects
|
7/17
|
10/17
|
-
|
-
|
High
|
Changed to little uncertainty
|
|
Poisoning fatalities
|
-
|
4/17
|
7/17
|
6/17
|
Moderate
|
Upgraded for very strong association
|
|
Stroke
|
15/17
|
2/17
|
-
|
-
|
High
| |
|
Extracranial hemorrage
|
16/16
|
-
|
-
|
-
|
High
| |
|
All cause mortality
|
12/17
|
5/17
|
-
|
-
|
-
|
Agreed to remove this outcome
|
|
Pain at rest
|
16/17
|
1/17
|
-
|
-
|
High
| |
|
Pain ay motion
|
15/17
|
2/17
|
-
|
-
|
Moderate
|
Uncertainty about directness of outcome measure
|
|
Mobility
|
3/17
|
14/17
|
-
|
-
|
Moderate
| |
|
Quality of life
|
1/17
|
11/17
|
5/17
|
-
|
Moderate
| |
|
Dropout due to side effects
|
14/17
|
3/17
|
-
|
-
|
High
| |
|
Serious gi complications
|
-
|
3/17
|
8/17
|
6/17
|
-
|
Need more information before consensus
|
|
All cause mortality
|
2/17
|
15/17
|
-
|
-
|
Moderate
| |
|
Non-fatal stroke
|
17/17
|
-
|
-
|
-
|
High
| |
|
Non-fatal MI
|
17/17
|
-
|
-
|
-
|
High
| |
|
Death
|
13/17
|
4/17
|
-
|
-
|
High
| |
|
Non-fatal MI
|
11/16
|
5/16
|
-
|
-
|
High
| |
|
All cause death
|
12/17
|
5/17
|
-
|
-
|
Moderate
|
If reporting bias, otherwise high
|
|
Major bleeding
|
15/17
|
2/17
|
-
|
-
|
High
| |
|
Recurrent thromboembolism
|
6/17
|
11/17
|
-
|
-
|
High
| |
|
Clinical cure
|
-
|
13/17
|
4/17
|
-
|
Moderate
| |
|
Dropout due to side effects
|
-
|
10/17
|
7/17
|
-
|
Moderate
| |
|
Relapse
|
2/17
|
11/17
|
4/17
|
-
|
Moderate
| |
|
Tuberculosis
|
2/17
|
10/17
|
5/17
|
-
|
Moderate
| |
|
TB death
|
8/17
|
8/17
|
1/17
|
-
|
High
| |
|
TB meningitis
|
1/17
|
4/17
|
12/17
|
-
|
Moderate
|
Strong association
|
|
Serious adverse events
|
1/12
|
-
|
-
|
11/12
|
-
|
No data, outcome removed
|
|
Condition unchanged
|
5/17
|
19/17
|
2/17
|
-
|
-
|
No consensus regarding sparse data
|
|
Poor outcome- surgeon rated
|
9/17
|
8/17
|
-
|
-
|
-
|
Need bias information before consensus
|
|
2nd procedure needed
|
9/17
|
8/17
|
-
|
-
|
Moderate
| |
|
No success – objective rater
|
5/17
|
10/17
|
2/17
|
-
|
-
|
No consensus regarding sparse data
|
|
Risks & side effects
|
1/15
|
2/15
|
2/15
|
10/15
|
-
|
No data, outcome removed
|
|
Dental caries – start
|
-
|
-
|
8/17
|
9/17
|
Very low
| |
|
Dental caries – stop
|
-
|
-
|
5/17
|
12/17
|
Very low
| |
|
Dental florosis
|
-
|
1/17
|
3/17
|
13/17
|
Very low
| |
|
Bone fracture
|
-
|
1/17
|
3/17
|
13/17
|
Very low
| |
|
Cancer mortality
|
-
|
1/17
|
2/17
|
14/17
|
Very low
| |
|
All injuries
|
-
|
1/17
|
12/17
|
4/17
|
Very low
|
Question changed
|
|
Correct use early
|
8/17
|
5/17
|
4/17
|
-
|
High
|
Question changed
|
|
Correct use follow up
|
2/17
|
8/17
|
6/17
|
1/17
|
High
|
Question changed
|
|
Possession of seat
|
7/17
|
6/17
|
3/17
|
-
|
High
|
Question changed
|
|
CHD
|
11/13
|
2/13
|
-
|
-
|
High
| |
|
Breast cancer
|
11/13
|
2/13
|
-
|
-
|
High
| |
|
Stroke
|
11/13
|
2/13
|
-
|
-
|
High
| |
|
Colorectal cancer
|
11/13
|
2/13
|
-
|
-
|
High
| |
|
Endometrial cancer
|
11/13
|
2/13
|
-
|
-
|
High
| |
|
Hip fracture
|
11/13
|
2/13
|
-
|
-
|
High
| |
