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Table 1 "Patients-to-be-treated " by type of treatment, based on proportion of patients with a contraindication and intolerance (n = 286)

From: Assessing the impact of heart failure specialist services on patient populations

 

Proportion with contra-indication (Pci)

Prop. intolerant (Pint)

Proportion eligible Pe = 1 - (Pci + Pint)

Proportion already treated (Pt)

Pe-u (= Pe - Pt)

Incremental number of "patients-to-be-treated" (= n * Pe-u)

Spironolactone

0.08* (95% CI 0.04–0.15)

0.08 [10] (95% CI 0.06–0.1)

0.84

0.25* (95% CI 0.18–0.34)

0.59

169

b-blockers

0.2* (95% CI 0.13–0.28)

0.052 [29] (95% CI 3.9–6.5)

0.748

0.12* (95% CI 0.07–0.19)

0.628

180

N-LEI

0*

0.15**

0.85

0

0.85

243

  1. *Estimates from local audit data **Based on informed judgment-see methods