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Table 2 Epidemiological model for outcomes research to evaluate practice guidelines

From: Outcomes research in the development and evaluation of practice guidelines

Outcome =

Exposure +

Confounders +

Error

• Clinical outcomes (for example, disease development, complications)

• Practice patterns

• Extraneous factors that can influence practice patterns and outcomes, that is, initial conditions

• Misclassification of diagnosis, practice patterns and outcomes

• Quality

  

• Error in measurement of practice patterns and outcomes

• Cost

   

• Appropriateness

  

• Unmeasured factors