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Table 4 Variation in the odds ratio of being prescribed the first line NICE recommended monotherapy among hypertensive patients without cardiovascular comorbidity*

From: Impact of ethnic-specific guidelines for anti-hypertensive prescribing in primary care in England: a longitudinal study

 

All hypertensive patients

Newly registered hypertensive patients

Variable

Odds ratio

95% CI‡

P value

Odds ratio

95% CI

P value

NICE2

1.44

1.19–1.75

<0.0001

1.62

1.10–2.36

0.013

References period between 2000–2005

      

Interaction term NICE* guidelines groups

      

Younger non–black patients* NICE

1.49

1.17–1.91

0.001

1.83

1.17–2.87

0,008

Older non black patients* NICE

0.58

0.46–0.74

<0.0001

0.56

0.39–0.77

0.001

Reference

      

Black patients* period between 2000–2005

      

NICE patients groups

      

Younger non–black patients

0.16

0.12–0.21

<0.0001

0.12

0.07–0.19

<0.0001

Older non–black patients

0.49

0.37–0.65

<0.0001

0.55

0.39–0.77

0.001

Reference non–black patients

      

Year

1.02

0.98–1.05

0.247

1.10

1.01–1.20

0.037

Sex

0.89

0.79–1.00

0.079

1.00

0.84–1.19

0.977

Reference female

      

BHS3

1.06

0.98–1.15

0.119

0.85

0.65–1.08

0.190

Reference period between 2000 and 2003

      
  1. 1Based on the 2006 NICE hypertension guideline update reference 24.
  2. *Patients without one of the follow disease: coronary heart disease, diabetes mellitus, heart failure, atrial fibrillation, disease, stroke or renal failure.
  3. ‡CI confidence interval.
  4. 2NICE a variable which stands for the period after introduction of the 2006 NICE guidelines 2006–2007.
  5. 3BHS a variable which stands for the period after the introduction of the 2004 BHS guidelines 2004–2007.