Modeling the impact of the 7-valent pneumococcal conjugate vaccine in Chinese infants: an economic analysis of a compulsory vaccination

Table 2 **Cost* and utility of pneumococcal disease in Chinese children ≤5 years of age**

Variable	Base-case estimate	Ranges for sensitivity analysis	Source
Cost
Bacteremia per episode	2666.67	793.65–6349.21	Estimated
Meningitis per episode	3587.3	476.19–7936.51	Estimated
Pneumonia per episode	607.3	158.73–1587.3	Estimated
AOM per episode	111.11	31.75–317.46	Estimated
Tympanostomy caused by AOM	333.33	Base ± 25%	Estimated
Hearing aids per unit	634.92	300–1200	Estimated
Replacement interval (years)	6	3–10	Estimated
Special education for disability per year	2557.84	158.73–3174.6	Estimated
PCV-7 cost per dose	136.51	102.38–170.63	Estimated
Cost of vaccine administration	1.86	0–3.17	Estimated
Salary per day	22.6	6.3–27.64	Estimated
Work-lost days for disease
Bacteremia	8	6–10	Estimated
Meningitis	9	6–12	Estimated
Pneumonia	7	5–9	Estimated
AOM	5	4–8	Estimated
Utility
Bacteremia	0.9921	Base ± 25%	[46–49]
Meningitis	0.9768	Base ± 25%	[46–49]
Pneumonia	0.9921	Base ± 25%	[46–49]
AOM	0.995	Base ± 25%	[46–49]
Tympanostomy caused by AOM	0.82	Base ± 25%	[46–49]
Long-term disability	0.6	Base ± 25%	[46–49]
Long-term deafness	0.8	Base ± 25%	[46–49]
Death	0	-	[46–49]

*Costs are presented in US dollars (January 2012 exchange rate, US$ = CYN 6.30).

ISSN: 1472-6963