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Table 2 Type and quality of cancer services for the “before” and “after” periods, in the reference centre and in the two peripheral centres

From: Organizing medical oncology care at a regional level and its subsequent impact on the quality of early breast cancer management: a before-after study

  Overall   Reference centre   Peripheral centres  
  Before After p Before After p Before After p
Description          
Surgery    1.00    1.00    0.96
Yes 305 (99.7) 360 (99.7)   149 (100.0) 193 (100.0)   156 (99.4) 167 (99.4)  
No 1 (0.3) 1 (0.3)   0 (0.0) 0 (0.0)   1 (0.6) 1 (0.6)  
Chemotherapy    0.07    0.45    0.04
Yes 151 (49.3) 152 (42.2)   79 (53.0) 94 (48.7)   72 (45.9) 58 (34.7)  
No 155 (50.7) 208 (57.8)   70 (46.9) 99 (51.3)   85 (54.1) 109 (65.3)  
Exposition to taxane    <0.0001    <0.0001    <0.0001
Yes 90 (59.6) 149 (98.0)   51 (64.6) 93 (98.9)   39 (54.2) 56 (96.6)  
No 61 (40.4) 3 (2.0)   28 (35.4) 1 (1.1)   33 (45.8) 2 (3.4)  
Hormone therapy    0.84    0.51    0.63
Yes 251 (82.3) 293 (81.4)   118 (79.7) 148 (76.7)   133 (84.7) 145 (86.8)  
No 54 (17.7) 67 (18.6)   30 (20.3) 45 (23.3)   24 (15.3) 22 (13.2)  
Radiotherapy    0.59    0.84    0.35
Yes 281 (91.8) 327 (90.6)   136 (91.3) 178 (92.2)   145 (92.4) 149 (88.7)  
No 25 (8.2) 34 (9.4)   13 (8.7) 15 (7.8)   12 (7.6) 19 (11.3)  
Delayed treatment (>12 weeks)    0.81    0.85    0.93
No 302 (98.7) 357 (98.9)   148 (99.3) 192 (99.5)   154 (98.1) 165 (98.2)  
Yes 4 (1.3) 4 (1.1)   1 (0.7) 1 (0.5)   3 (1.9) 3 (1.8)  
Time between surgery and adjuvant chemotherapy (weeks) 6.0 ± 3.0 5.6 ± 3.6 0.11 5.1 ± 2.2 5.3 ± 3.7 0.87 6.7 ± 3.4 6.0 ± 3.4 0.17
4.9 [1.0-20.4] 4.9 [0.3-31.7]   4.6 [1.6-15.4] 4.6 [0.3-31.7]   6.6 [1.0-20.4] 5.3 [1.1-17.1]  
Dose-dense    0.22    0.60    0.32
Yes 126 (86.3) 113 (91.1)   70 (90.9) 69 (93.2)   56 (81.2) 44 (88.0)  
No 20 (13.7) 11 (8.9)   7 (9.1) 5 (6.8)   13 (18.8) 6 (12.0)  
24-month progression free survival (%) 96.8 95.6 0.79 95.2 96.7 0.68 96.6 94.0 0.93