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Table 5 Total and monthly drugs cost of mCRPC by type of medication

From: Drug costs in the management of metastatic castration-resistant prostate cancer in Canada

  Total mCRPC cost per patient Monthly mCRPC cost per patient Total mCRPC cost in Canada
Current model Mean (95%CI) Median (IQR) Mean (95%CI) (annual cohort of 4,000 mCRPC patients)
Medication type:     
  Primary medication* $23,745 ($23,238-$24,253) $13,316 ($939-$41,553) $845 ($827-$882) $94,980,000 49.1%
  Medication for medical castration $9,898 ($9,779-$10,016) $8,811 ($4,934-$14,098) $352 ($348-$357) $39,592,000 20.4%
  Bone-targeted therapy $14,785 ($14,607-$14,963) $13,163 ($7,371-$21,060) $526 ($520-$532) $59,032,000 30.5%
Total cost of mCRPC $48,428 ($47,624-$49,232) $35,290 ($13,244-$76,711) $1,723 ($1,695-$1,752) $193,604,000 100.0%
Alternate model      
Medication type:      
  Primary medication** $71,302 ($70,026-$72,579) $62,816 ($939-$123,501) $1,912 ($1,877-$1,946) $285,208,000 68.5%
  Medication for medical castration $13,140 ($12,971-$13,309) $11,983 ($5,639-$19,737) $352 ($348-$357) $52,560,000 12.6%
  Bone-targeted therapy $19,629 ($19,376-$19,882) $17,901 ($8,424-$29,484) $526 ($520-$532) $78,516,000 18.9%
Total cost of mCRPC $104,071 ($102,373-$105,770) $92,700 ($15,002-$172,722) $2,790 ($2,745-$2,835) $416,284,000 100.0%
  1. Abbreviations: 95%CI 95% confidence interval, IQR Interquartile range;
  2. *includes AA, docetaxel and abitarerone;
  3. **includes AA, abitarerone, docetaxel and cabazitaxel;
  4. assuming that only 95% of patients have received medication for medical castration;
  5. assuming that only 90% of patients have received bone-targeted therapy.
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