Table 5 Total and monthly drugs cost of mCRPC by type of medication
From: Drug costs in the management of metastatic castration-resistant prostate cancer in Canada
| Â | Total mCRPC cost per patient | Monthly mCRPC cost per patient | Total mCRPC cost in Canada | ||
|---|---|---|---|---|---|
Current model | Mean (95%CI) | Median (IQR) | Mean (95%CI) | (annual cohort of 4,000 mCRPC patients) | |
Medication type: | Â | Â | Â | Â | |
  Primary medication* | $23,745 ($23,238-$24,253) | $13,316 ($939-$41,553) | $845 ($827-$882) | $94,980,000 | 49.1% |
  Medication for medical castration†| $9,898 ($9,779-$10,016) | $8,811 ($4,934-$14,098) | $352 ($348-$357) | $39,592,000 | 20.4% |
  Bone-targeted therapy‡ | $14,785 ($14,607-$14,963) | $13,163 ($7,371-$21,060) | $526 ($520-$532) | $59,032,000 | 30.5% |
Total cost of mCRPC | $48,428 ($47,624-$49,232) | $35,290 ($13,244-$76,711) | $1,723 ($1,695-$1,752) | $193,604,000 | 100.0% |
Alternate model | Â | Â | Â | Â | Â |
Medication type: | Â | Â | Â | Â | Â |
  Primary medication** | $71,302 ($70,026-$72,579) | $62,816 ($939-$123,501) | $1,912 ($1,877-$1,946) | $285,208,000 | 68.5% |
  Medication for medical castration†| $13,140 ($12,971-$13,309) | $11,983 ($5,639-$19,737) | $352 ($348-$357) | $52,560,000 | 12.6% |
  Bone-targeted therapy‡ | $19,629 ($19,376-$19,882) | $17,901 ($8,424-$29,484) | $526 ($520-$532) | $78,516,000 | 18.9% |
Total cost of mCRPC | $104,071 ($102,373-$105,770) | $92,700 ($15,002-$172,722) | $2,790 ($2,745-$2,835) | $416,284,000 | 100.0% |