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Table 7 Comparison of pediatric formulation derived costs to the WHO Global Price Reporting Mechanism (GPRM) database

From: Estimating age-based antiretroviral therapy costs for HIV-infected children in resource-limited settings based on World Health Organization weight-based dosing recommendations

Medication (strength) Monthly costs for 6–9.9 kg Monthly costs for 10–13.9 kg Monthly costsA
From GPRM
(Table 3) (Table 3)
ABC (20 mg/ml) $14.59 $21.89 $15.84
ABC (60 mg) $8.21 $10.94 $12.36
d4T (1 mg/ml) $5.47 NR $4.56
d4T (15 mg) NR $1.22 $1.44
3TC (10 mg/ml) $2.43 $3.65 $2.06
LPV/r (80/20 mg/ml) $17.33 $23.10 $11.81
LPV/r (100/25 mg) NR $12.77 $11.20
NVP (10 mg/ml) $4.86 $6.08 $4.81
NVP (50 mg) $4.10 $5.47 N/A
ZDV (10 mg/ml) $5.47 $7.30 $4.82
ZDV (60 mg) $4.56 $6.08 N/A
ZDV/3TC (60 mg/30 mg) $4.56 $6.08 $5.60
ZDV/3TC/NVP (60 mg/30 mg/50 mg) $6.38 $8.51 $8.28
d4T/3TC (6 mg/30 mg) $2.74 $3.65 $3.79
d4T/3TC/NVP (6 mg/30 mg/50 mg) $3.65 $4.86 $4.66
ABC/3TC (60 mg/30 mg) $8.21 $10.94 $13.96
  1. Abbreviations: ABC abacavir, d4T stavudine, 3TC lamivudine, EFV efavirenz, LPV/r lopinavir/ritonavir, NVP nevirapine, ZDV zidovudine, mg milligrams, ml milliliter, NR not recommended, N/A not applicable (no cost estimate was available from the GPRM for this formulation).
  2. A. Pediatric formulations in the WHO GPRM are based on costs for a 10 kg child. We have shown our calculations from Table 3 for weight bands 6–9.9 kg and 10–13.0 kg as a comparison.