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Table 7 Comparison of pediatric formulation derived costs to the WHO Global Price Reporting Mechanism (GPRM) database

From: Estimating age-based antiretroviral therapy costs for HIV-infected children in resource-limited settings based on World Health Organization weight-based dosing recommendations

Medication (strength)

Monthly costs for 6–9.9 kg

Monthly costs for 10–13.9 kg

Monthly costsA

From GPRM

(Table 3)

(Table 3)

ABC (20 mg/ml)

$14.59

$21.89

$15.84

ABC (60 mg)

$8.21

$10.94

$12.36

d4T (1 mg/ml)

$5.47

NR

$4.56

d4T (15 mg)

NR

$1.22

$1.44

3TC (10 mg/ml)

$2.43

$3.65

$2.06

LPV/r (80/20 mg/ml)

$17.33

$23.10

$11.81

LPV/r (100/25 mg)

NR

$12.77

$11.20

NVP (10 mg/ml)

$4.86

$6.08

$4.81

NVP (50 mg)

$4.10

$5.47

N/A

ZDV (10 mg/ml)

$5.47

$7.30

$4.82

ZDV (60 mg)

$4.56

$6.08

N/A

ZDV/3TC (60 mg/30 mg)

$4.56

$6.08

$5.60

ZDV/3TC/NVP (60 mg/30 mg/50 mg)

$6.38

$8.51

$8.28

d4T/3TC (6 mg/30 mg)

$2.74

$3.65

$3.79

d4T/3TC/NVP (6 mg/30 mg/50 mg)

$3.65

$4.86

$4.66

ABC/3TC (60 mg/30 mg)

$8.21

$10.94

$13.96

  1. Abbreviations: ABC abacavir, d4T stavudine, 3TC lamivudine, EFV efavirenz, LPV/r lopinavir/ritonavir, NVP nevirapine, ZDV zidovudine, mg milligrams, ml milliliter, NR not recommended, N/A not applicable (no cost estimate was available from the GPRM for this formulation).
  2. A. Pediatric formulations in the WHO GPRM are based on costs for a 10 kg child. We have shown our calculations from Table 3 for weight bands 6–9.9 kg and 10–13.0 kg as a comparison.