Table 3 Adjusted odds ratios for chemotherapy- induced neutropenic complications requiring inpatient care in subgroup and secondary analyses

Narrow definition of CINC

 Days of Filgrastim Prophylaxis

1-3

8,371

130

1.6%

1.15 (0.77,1.72)

1.60 (1.05,2.45)

4-6

3,691

67

1.8%

1.35 (0.88,2.09)

1.74 (1.11,2.72)

> = 7

2,226

30

1.3%

–

–

Broad definition of CINC

 First cycle only

  Days of Filgrastim Prophylaxis

1-3

1,054

74

7.0%

1.37 (0.81, 2.30)

1.56 (0.89, 2.74)

4-6

482

24

5.0%

0.95 (0.51, 1.76)

1.11 (0.58, 2.12)

> = 7

363

19

5.2%

–

–

 Breast cancer

  Days of Filgrastim Prophylaxis

1-3

4,038

94

2.3%

1.44 (0.86, 2.39)

1.75 (1.02, 3.00)

4-6

1,829

49

2.7%

1.66 (0.96, 2.86)

1.92 (1.09, 3.38)

> = 7

1,103

18

1.6%

–

–

 Lung cancer

  Days of Filgrastim Prophylaxis

1-3

630

44

7.0%

13.52 (1.85, 98.79)

20.20 (1.92, 212.36)

4-6

349

15

4.3%

8.08 (1.06, 61.70)

14.54 (1.33, 158.65)

> = 7

181

1

0.6%

–

–

 Colorectal cancer

  Days of Filgrastim Prophylaxis

1-3

1,327

21

1.6%

1.64 (0.22, 12.32)

1.88 (0.21, 16.67)

4-6

360

9

2.5%

2.62 (0.33, 20.89)

2.54 (0.27, 23.54)

>=7

103

1

1.0%

–

–

 NHL

  Days of Filgrastim Prophylaxis

1-3

830

63

7.6%

1.86 (1.13, 3.05)

2.06 (1.19, 3.55)

4-6

474

28

5.9%

1.42 (0.80, 2.52)

1.76 (0.95, 3.23)

> = 7

519

22

4.2%

–

–