Table 2 Total costs, LYs and QALYs of all interventions for HBeAg positive CHB patients aged 30Â years old and above
Interventions | Total costs (THB)§ | LYs | QALYs | Incremental cost (THB) | Incremental QALYs | ICER per QALY gained |
|---|---|---|---|---|---|---|
First drug (Second drug) Third drug | ||||||
1. Generic lamivudine (tenofovir)†| 456,000 | 20.87 | 13.66 | -72,000 | 5.03 | Dominant* |
2. Generic lamivudine (tenofovir)‡ | 490,000 | 20.87 | 13.66 | -38,000 | 5.03 | Dominant* |
3. Tenofovir monotherapy†| 501,000 | 20.89 | 13.67 | -26,000 | 5.04 | Dominant* |
4. Palliative care | 527,000 | 13.13 | 8.63 | - | - | - |
5. Original lamivudine (tenofovir)†| 937,000 | 20.87 | 13.66 | 409,000 | 5.03 | 81,000 |
6. Pegylated interferon (original lamivudine) tenofovir†| 953,000 | 20.89 | 13.67 | 426,000 | 5.05 | 84,000 |
7. Original lamivudine (tenofovir)‡ | 971,000 | 20.87 | 13.66 | 444,000 | 5.03 | 88,000 |
8. Generic lamivudine (adefovir)†| 982,000 | 20.87 | 13.66 | 454,000 | 5.03 | 90,000 |
9. Pegylated interferon (tenofovir)†| 1,057,000 | 20.91 | 13.69 | 530,000 | 5.06 | 105,000 |
10. Telbivudine (tenofovir)†| 1,091,000 | 20.90 | 13.68 | 564,000 | 5.05 | 112,000 |
11. Generic lamivudine (adefovir)‡ | 1,134,000 | 20.87 | 13.66 | 606,000 | 5.03 | 121,000 |
12. Telbivudine (tenofovir)‡ | 1,134,000 | 20.87 | 13.66 | 606,000 | 5.03 | 121,000 |
13. Pegylated interferon (original lamivudine) tenofovir†| 1,325,000 | 20.89 | 13.67 | 798,000 | 5.05 | 158,000 |
14. Adefovir (generic lamivudine)†| 1,364,000 | 20.85 | 13.64 | 837,000 | 5.01 | 167,000 |
15. Pegylated interferon (lamivudine) adefovir†| 1,371,000 | 20.89 | 13.67 | 844,000 | 5.05 | 167,000 |
16. Telbivudine (adefovir)†| 1,429,000 | 20.90 | 13.68 | 902,000 | 5.05 | 178,000 |
17. Pegylated interferon (telbivudine) tenofovir†| 1,442,000 | 20.92 | 13.69 | 915,000 | 5.06 | 181,000 |
18. Original lamivudine (adefovir)†| 1,463,000 | 20.87 | 13.66 | 936,000 | 5.03 | 186,000 |
19. Entecavir (tenofovir)†| 1,519,000 | 20.88 | 13.67 | 991,000 | 5.04 | 197,000 |
20. Entecavir (adefovir)†| 1,536,000 | 20.88 | 13.67 | 1,009,000 | 5.04 | 200,000 |
21. Adefovir (original lamivudine)†| 1,564,000 | 20.85 | 13.64 | 1,037,000 | 5.01 | 207,000 |
22. Original lamivudine (adefovir)‡ | 1,616,000 | 20.87 | 13.66 | 1,088,000 | 5.03 | 216,000 |
23. Pegylated interferon (adefovir) generic lamivudine†| 1,648,000 | 20.88 | 13.66 | 1,120,000 | 5.04 | 222,000 |
24. Telbivudine (adefovir)‡ | 1,657,000 | 20.90 | 13.68 | 1,130,000 | 5.05 | 224,000 |
25. Pegylated interferon (telbivudine) adefovir†| 1,710,000 | 20.92 | 13.69 | 1,182,000 | 5.06 | 233,000 |
26. Pegylated interferon (original lamivudine) adefovir†| 1,744,000 | 20.89 | 13.67 | 1,216,000 | 5.05 | 241,000 |
27. Pegylated interferon (entecavir) tenofovir†| 1,771,000 | 20.90 | 13.68 | 1,243,000 | 5.05 | 246,000 |
28. Pegylated interferon (entecavir) adefovir†| 1,785,000 | 20.90 | 13.68 | 1,257,000 | 5.05 | 249,000 |
29. Pegylated interferon (adefovir) original lamivudine†| 1,812,000 | 20.88 | 13.66 | 1,284,000 | 5.04 | 255,000 |