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Table 1 Characteristics of patients treated with febrile neutropenia

From: Time to antibiotics and outcomes in cancer patients with febrile neutropenia

Clinical variables Total patients N = 105 (%) High risk patients N = 37 (%) Low risk patients N = 68 (%) P value
Median age yrs 60 (18–89) 66 (46–86) 55 (18–89) 0.058
Age over 65 36 (34) 22 (60) 14 (21) <0.001
Male 43 (41) 21 (57) 22 (32) 0.01
MASCC score 21 ± 2.5 18 ± 1.3 23 ± 1.5 0.15
Comorbid illness 52 (49) 32 (86) 20 (29) <0.001
Diabetes mellitus 12 (11) 8 (22) 4 (6) 0.02
Chronic renal failure 4 (4) 3 (8) 1 (2) 0.12
Hematological malignancies 46 (44) 19 (51) 27 (40) 0.17
Advanced disease 63 (60) 24 (65) 39 (57) 0.29
Prophylactic filgrastim & or antibiotics 50 (48) 17 (46) 33 (49) 0.48
Mean SBP mmHg 123 ± 22 120 ± 21 124 ± 23 0.71
Mean heart rate bpm 105 ± 20 101 ± 17 107 ± 21 0.97
Mean O2 saturation% 97 ± 2 97 ± 2 97 ± 2 0.76
Mean WBC 109/l 0.83 ± 2.8 1.5 ± 4.8 0.99 ± 0.69 0.056
Mean ANC 109/l 0.21 ± 0.23 0.21 ± 0.18 0.21 ± 0.25 0.08
Mean hemoglobin g/L 98 ± 21 97 ± 18 102 ± 23 0.20
Mean platelet count 109/l 136 ± 102 127 ± 106 156 ± 98 0.004
Mean serum sodium mEq/L 135 ± 3 134 ± 3 134 ± 4 0.60
Mean serum creatinine μmol/L 69 ± 36 99 ± 50 68 ± 16 <0.001
Mean BUN mmol/L 5 ± 4.2 8.6 ± 5.3 4.7 ± 2.6 <0.001
Median TAA hrs (range) 2.5 (0.03-50) 3 (0.22-19) 2.5 (0.03-50) 0.16
  1. ANC = absolute neutrphil count, BUN = blood urea nitrogen, TAA = time to antibiotics administration, WBC = white blood cell, ± standard deviation.