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Table 4 The five most frequent ADE codes in England, Germany and USA, in descending order

From: International prevalence of adverse drug events in hospitals: an analysis of routine data from England, Germany, and the USA

Code Title Category Number of inpatients
Germany
A04.7 Enterocolitis due to Clostridium difficile C 36,215
D69.58 Other secondary thrombocytopenia, not classified as transfusion-refractory C 32,600
D70.10 Drug-induced agranulocytosis and neutropenia: critical phase < 10 days A.1 16,044
D61.10 Drug-induced aplastic anemia A.1 14,002
D69.59 Secondary thrombocytopenia not otherwise specified C 12,560
England
A04.7 Enterocolitis due to Clostridium difficile C 33,509
T39.1 Poisoning by 4-aminophenol derivatives B.1 27,208
T43.2 Poisoning by other and unspecified antidepressants B.1 8,231
T39.3 Poisoning by other nonsteroidal anti-inflammatory drug (NSAID) B.1 8,051
T42.4 Poisoning by benzodiazepines B.1 8,035
USA
008.45 Intestinal infection due to Clostridium difficile C 56,771
287.4 Secondary thrombocytopenia C 22,700
969.4 Poisoning by benzodiazepine-based tranquilizers B.1 12,683
969.0 Poisoning by antidepressants B.1 7,332
965.4 Poisoning by aromatic analgesics, not elsewhere classified B.1 5,119
  1. Translation from the German by the author.