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Table 4 The five most frequent ADE codes in England, Germany and USA, in descending order

From: International prevalence of adverse drug events in hospitals: an analysis of routine data from England, Germany, and the USA

Code

Title

Category

Number of inpatients

Germany

A04.7

Enterocolitis due to Clostridium difficile

C

36,215

D69.58

Other secondary thrombocytopenia, not classified as transfusion-refractory

C

32,600

D70.10

Drug-induced agranulocytosis and neutropenia: critical phase < 10 days

A.1

16,044

D61.10

Drug-induced aplastic anemia

A.1

14,002

D69.59

Secondary thrombocytopenia not otherwise specified

C

12,560

England

A04.7

Enterocolitis due to Clostridium difficile

C

33,509

T39.1

Poisoning by 4-aminophenol derivatives

B.1

27,208

T43.2

Poisoning by other and unspecified antidepressants

B.1

8,231

T39.3

Poisoning by other nonsteroidal anti-inflammatory drug (NSAID)

B.1

8,051

T42.4

Poisoning by benzodiazepines

B.1

8,035

USA

008.45

Intestinal infection due to Clostridium difficile

C

56,771

287.4

Secondary thrombocytopenia

C

22,700

969.4

Poisoning by benzodiazepine-based tranquilizers

B.1

12,683

969.0

Poisoning by antidepressants

B.1

7,332

965.4

Poisoning by aromatic analgesics, not elsewhere classified

B.1

5,119

  1. Translation from the German by the author.