Source | Target for BP or lipid management | Outcome |
---|---|---|
The MEDMAN study [15], 2007 | BP: < 140/85Â mmHg | No significant difference |
Faulkner [16], 2000 | LDL-C: ≤ 100 mg/dL (2.6 mmol/L) | No significant difference at 6 or 12 weeks |
More patients achieved target in intervention than in control at 1 and 2 years (P < 0.05) | ||
Olson [17], 2009 | LDL-C and non-HDL-C: < 100 mg/dL (2.6 mmol/L) and < 130 mg/dL (3.3 mmol/L) for all patients, < 70 mg/dL (1.8 mmol/L) and < 100 mg/dL (2.6 mmol/L) for patients with diabetes, multivessel coronary disease, at least 1 recurrent coronary event, or current smokers | No significant difference in maintaining LDL-C and non-HDL-C goal, and BP goal of < 130 mmHg |
BP: < 140/90 mmHg for all patients, <130/80 mmHg for patients with diabetes or CKD | More patients maintained a BP goal of < 140 mmHg in intervention than in control (P = 0.03) | |
Straka [18], 2005 | LDL-C: ≤ 100 mg/dL (2.6 mmol/L) | More patients achieved LDL-C goal in intervention than in control at 6.5 months and the following 18 months (P < 0.001) |