Population | Data | Unit | Classen 1991[17] | Bates 1993[14] | Bates 1995[15] | Lazarus 2003[18] | Berga Cullere 2008[16] | Morimoto 2011[19] |
---|---|---|---|---|---|---|---|---|
Surgical | Records | Admissions | 23,458* | 151‡ | 493‡ | - | - | 1,469 |
Patients | - | - | - | - | 775 | - | ||
Patient-days | - | 1,066 | 4,339 | - | - | - | ||
No. ADEs | ADEs | 480 | 5 | 39* | - | - | 407 | |
Patients with ADE | - | - | - | - | 69 | - | ||
Occurrence ADEs (95% CI) | /100 admissions | 2.0 (1.9-2.2)* | 3.3 (0.5-6.2)‡ | 7.9 (5.5-10.3)‡ | - | - | 27.7 (25.4-30.0) | |
/100 patients | - | - | - | - | 8.9 (6.9-10.9)* | - | ||
/1,000 patient-days | - | 4.7 (1.5-10.9)* | 8.9 (6.1-11.7) | - | - | - | ||
Preventability ADEs | Â | - | - | 7/39 (18% (5.9-30.0))* | - | 37/69 (54% (41.9-65.4) of the ADE patients) | - | |
Nonsurgical | Records | Admissions | 8,064* | 142‡ | 527‡ | - | - | 1,531 |
Patients | - | - | - | - | 775 | - | ||
Patient-days | - | 1,003 | 11,499 | - | - | - | ||
No. ADEs | ADEs | 251 | 13 | 122* | - | - | 504 | |
Patients with ADE | - | - | - | - | 90 | - | ||
Occurrence ADEs (95% CI) | /100 admissions | 3.1 (2.7-3.5)* | 9.2 (4.4-13.9)‡ | 23.1 (19.5-26.8)‡ | - | - | 32.9 (30.6-35.3) | |
/100 patients | - | - | - | - | 11.6 (9.4-13.9)* | - | ||
/1,000 patient-days | - | 13.0 (6.9-22.2)* | 10.6 (8.7-12.4) | - | - | - | ||
Preventability ADEs | Â | - | - | 34/122 (28% (19.9-35.8))* | - | 45/90 (50% (39.7-60.3) of the ADE patients) | - | |
Overall | Records | Admissions | 36,653 | 420 | 4,031 | 4,320 †| - | 3,459 |
Patients | - | - | - | - | 1,550 | - | ||
Patient-days | - | 2,967 | 21,412 | - | - | - | ||
No. ADEs | ADEs | 731 | 27 | 247 | 98†| 194 | 1,010 | |
Patients with ADE | - | - | - | - | - | - | ||
Occurrence ADEs (95% CI) | /100 admissions | 2.0 (1.9-2.1)* | 6.4 (4.1-8.8)* | 6.1 (5.4-6.9) | 2.3 (1.8-2.7)†| - | 29.2 (27.7-30.7) | |
/100 patients | - | - | - | - | 12.5 (10.9-14.2)* | - | ||
/1,000 patient-days | - | - | - | - | - | - | ||
Preventability ADEs | Â | - | 15/27 (56%) | 70/247 (28%) | - | 91/194 (47%) | 141/1010 (14%) |