Table 1 Summary of patients’ demographic and clinical characteristics
Characteristics of study population | Experienced cohort 1 | Newly treated cohort 2 | ||||
|---|---|---|---|---|---|---|
(n = 1894) | Intervention | Control | p-value | Intervention | Control | p-value |
(n = 446) | (n = 352) | (n = 520) | (n = 576) | |||
Female (n = 1258) | 289 (64.8%) | 248 (70.5%) | 0.0908 | 337 (64.8%) | 384 (66.7%) | 0.5171 |
Mean age (95% CI) | 39.4 (38.3–40.5) | 38 (37.1–38.9) | 0.065 | 38.6 (37.7–39.5) | 39.2 (38.4–40.1) | 0.349 |
Marital status (%) | ||||||
Single | 72 (16.1%) | 43 (12.2%) | 0.1157 | 79 (15.2%) | 79 (13.7%) | 0.1987 |
Divorced/Widowed | 119 (26.7%) | 114 (32.4%) | 140 (26.9%) | 186 (32.3%) | ||
Married | 181 (40.6%) | 159 (45.2%) | 253 (48.7%) | 268 (46.5%) | ||
Weight at start of follow-up—mean (95% CI) | ||||||
Male | 58.5 (56.7,60.3) | 58.3 (56.8,59.9) | 0.8974 | 54.9 (53.5,56.3) | 57.3 (56,58.5) | 0.0144 |
Female | 54.8 (53.5,56.0) | 55 (53.9,56.1) | 0.796 | 52.3 (51.1,53.5) | 52.8 (51.7,53.8) | 0.5529 |
WHO stage at ART initiation (%) | ||||||
Stage 1 | 14 (3.1%) | 46 (13.1%) | <0.0001 | 50 (9.6%) | 88 (15.3%) | 0.0003 |
Stage 2 | 61 (13.7%) | 84 (23.9%) | 146 (28.1%) | 199 (34.5%) | ||
Stage 3 | 278 (62.3%) | 172 (48.9%) | 247 (47.5%) | 224 (38.9%) | ||
Stage 4 | 31 (7%) | 22 (6.3%) | 31 (6%) | 21 (3.6%) | ||
CD4 value at ART initiation—mean (95% CI) | ||||||
CD4 value | 293 (269.1,316.9) | 334.3 (309.8,358.8) | 0.0183 | 169.2 (154.5,183.9) | 189.4 (176.1,202.7) | 0.0466 |
Evidence of adherence counselling prior to ART initiation | ||||||
Adherence counselling | 387 (86.8%) | 238 (67.6%) | <0.0001 | 457 (87.9%) | 401 (69.6%) | < 0.0001 |