| Utility values | Costs in € |
---|---|---|
Health State | Utility | Monthly Cost |
Healthy | 0.86 [17] | 0 |
Remission | 0.81 [17] | Direct: 35‡ |
Indirect: 173†| ||
Depressive Episode | 0.57 [17] | Direct: 190‡ |
Indirect: 380†| ||
Adverse Drug Reaction | Utility Decrease | Monthly cost* |
Constipation | 0.065 [33] | 12.5 |
Diarrhoea | 0.044 [33] | 5.5 |
Dyspepsia | 0.086 [33] | 12.0 |
Nausea | 0.065 [33] | 6.0 |
Somnolence | 0.085 [33] | 0.0 |
Headache | 0.115 [33] | 2.8 |
Sexual dysfunction | 0.049 [33] | 44.0 |
Sleep difficulties | 0.08095 [34] | 54.0 |
Discontinuation Symptoms | 0.065 [33] | 52.0 |
Study Medication | Expected Utility Decrease due to ADR § | Monthly medication cost ††|
Agomelatine | 0.026 | 60.27 |
Venlafaxine | 0.039 | 18.03 |
Escitalopram | 0.035 | 56.31 |
Fluoxetine | 0.026 | 21.31 |
Sertraline | 0.020 | 17.35 |
Generic Venlafaxine | Â | 14.38 |
Generic Escitalopram | Â | 45.60 |
Generic Fluoxetine | Â | 14.37 |
Generic Sertraline | Â | 10.81 |