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Table 6 Percentage change in variance of the estimate: complete cost collection vs. incomplete cost collection

From: Empirical analysis shows reduced cost data collection may be an efficient method in economic clinical trials

  Complete cost collection Incomplete cost collection
   Extrapolation Interpolation
  Alt 0a Alt 1b Alt 2c Alt 3d Alt 4e Alt 5f Alt 6d
Cost category (SD) (SD) shift (SD) shift (SD) shift (SD) shift (SD) shift (SD) shift
Sum of direct healthcare costs (936.67) (946.22) 1.02 (962.29) 2.74 (997.06) 6.45 (917.58) −2.04 (962.72) 2.78 (936.79) 0.01
Sum of direct non-healthcare costs (2568.91) (2534.07) −1.36 (2589.39) 0.80 (2598.16) 1.14 (2534.93) −1.32 (2611.32) 1.65 (2577.07) 0.32
Sum of costs (2864.38) (2827.43) −1.29 (2882.21) 0.62 (2893.05) 1.00 (2807.64) −1.98 (2911.74) 1.65 (2836.42) −0.89
  1. aAlternative 0, complete cost collection.
  2. bAlternative 1, incomplete cost collection, omitted quarter 2, replaced by quarter 3.
  3. cAlternative 2, incomplete cost collection, omitted quarter 3, replaced by quarter 4.
  4. dAlternative 3, incomplete cost collection, omitted quarters 2 and 3, replaced by quarter 4.
  5. eAlternative 4, incomplete cost collection, omitted quarter 2, replaced by quarters 1 and 3.
  6. fAlternative 5, incomplete cost collection, omitted quarter 3, replaced by quarters 2 and 4.
  7. gAlternative 6, incomplete cost collection, omitted quarters 2 and 3, replaced by quarters 1 and 4.