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Table 5 Complete cost collection vs. incomplete cost collection and interpolation (by the respective quarters), n=234

From: Empirical analysis shows reduced cost data collection may be an efficient method in economic clinical trials

 

Complete cost collection

Incomplete cost collection

  

Interpolation

  

Omitted quarters

 

Alt 0a

Alt 4b

Alt 5c

Alt 6d

   

Quarter 2 (by 1 and 3)

Quarter 3 (by 2 and 4)

Quarters 2 and 3 (by 1 and 4)

Cost category

means

(SD)

means

(SD)

means in difference

(StdErr)

means

(SD)

means in difference

(StdErr)

means

(SD)

means in difference

(StdErr)

Direct healthcare costs

      

 Physicians

523.38

(358.27)

508.40

(343.27)

14.97

(8.58)

527.56

(383.66)

4.19

(7.03)

501.87

(344.89)

21.51

(11.62)

 Physiotherapist

69.29

(162.63)

64.97

(164.25)

4.31

(3.23)

71.61

(175.50)

2.32

(2.83)

65.37

(185.64)

3.92

(5.42)

 Ambulatory clinic in hospital

35.79

(110.83)

37.93

(142.50)

2.14

(3.66)

28.62

(84.32)

7.18

(5.45)

25.88

(76.71)

*9.91

(5.88)

 Drugs

1315.52

(707.38)

1306.92

(701.52)

8.60

(7.23)

1304.79

(707.09)

*10.72

(5.75)

1276.92

(692.75)

**38.60

(12.53)

Sum of direct healthcare costs

1943.99

(936.67)

1918.23

(917.58)

**25.77

(11.82)

1932.58

(962.72)

11.41

(10.89)

1870.04

(936.79)

**73.95

(19.96)

Direct non-healthcare costs

      

 Outpatient nursing service

145.44

(593.85)

138.62

(546.78)

6.82

(11.98)

142.76

(608.39)

2.67

(7.35)

126.47

(537.84)

18.97

(20.85)

 Paid household help

418.46

(2455.42)

410.15

(2442.17)

8.30

(21.42)

415.96

(2494.90)

2.50

(17.83)

396.86

(2506.58)

21.60

(39.02)

Sum of direct non-healthcare costs

563.89

(2568.91)

548.77

(2534.93)

15.12

(23.25)

558.73

(2611.32)

5.17

(19.07)

523.33

(2577.07)

40.57

(39.89)

Sum of costs

2507.88

(2864.38)

2467.00

(2807.64)

40.89

(28.29)

2491.31

(2911.74)

16.58

(21.78)

2393.36

(2836.42)

**114.5

(47.70)

  1. *p-value of paired t-test/bootstrapping of differences between complete and incomplete cost collection <0.10.
  2. **p-value of paired t-test/bootstrapping of differences between complete and incomplete cost collection <0.05.
  3. aAlternative 0, complete cost collection.
  4. bAlternative 4, incomplete cost collection, omitted quarter 2, replaced by quarters 1 and 3.
  5. cAlternative 5, incomplete cost collection, omitted quarter 3, replaced by quarters 2 and 4.
  6. dAlternative 6, incomplete cost collection, omitted quarters 2 and 3, replaced by quarters 1 and 4.
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BMC Health Services Research

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