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Table 4 Complete cost collection vs. incomplete cost collection and extrapolation (by the respective quarter), n=234

From: Empirical analysis shows reduced cost data collection may be an efficient method in economic clinical trials

 

Complete cost collection

Incomplete cost collection

  

Extrapolation

  

Omitted quarters

 

Alt 0a

Alt 1b

Alt 2c

Alt 3d

   

Quarter 2 (by 3)

Quarter 3 (by 4)

Quarter 2 and 3 (by 4)

Cost category

mean

(SD)

mean

(SD)

mean difference

(StdErr)

mean

(SD)

mean difference

(StdErr)

mean

(SD)

mean difference

(StdErr)

Direct healthcare costs

 Physicians

523.38

(358.27)

517.57

(365.32)

5.81

(9.51)

525.99

(370.53)

2.62

(6.67)

522.75

(377.53)

0.63

(11.91)

 Physiotherapist

69.29

(162.63)

66.69

(166.77)

2.61

(3.78)

71.38

(178.98)

2.09

(3.33)

70.91

(202.65)

1.62

(6.73)

 Ambulatory clinic in hospital

35.79

(110.83)

42.89

(181.93)

7.10

(6.00)

28.60

(83.44)

7.19

(5.30)

28.41

(99.47)

7.38

(6.20)

 Drugs

1315.52

(707.38)

1312.68

(721.69)

2.84

(7.97)

1291.31

(709.17)

**24.21

(7.54)

1264.26

(739.52)

**51.26

(16.33)

Sum of direct healthcare costs

1943.99

(936.67)

1939.82

(946.22)

4.18

(14.01)

1917.28

(962.29)

**26.71

(12.04)

1886.32

(997.06)

**57.67

(22.20)

Direct non-healthcare costs

 Outpatient nursing service

145.44

(593.85)

140.63

(569.41)

4.81

(10.17)

135.29

(573.69)

10.15

(9.10)

120.36

(549.63)

25.08

(19.36)

 Paid household help

418.46

(2455.42)

416.48

(2433.88)

1.97

(20.61)

411.48

(2489.45)

6.97

(23.66)

402.53

(2527.39)

15.93

(45.70)

Sum of direct non-healthcare costs

563.89

(2568.91)

557.11

(2534.07)

6.78

(22.98)

546.77

(2589.39)

17.12

(24.27)

522.89

(2598.16)

41.00

(46.89)

Sum of costs

2507.88

(2864.38)

2496.93

(2827.43)

10.96

(28.11)

2464.05

(2882.21)

43.83

(27.12)

2409.21

(2893.05)

*98.67

(54.67)

  1. *p-value of paired t-test/bootstrapping of differences between complete and incomplete cost collection <0.10.
  2. **p-value of paired t-test/bootstrapping of differences between complete and incomplete cost collection <0.05.
  3. aAlternative 0, complete cost collection.
  4. bAlternative 1, incomplete cost collection, omitted quarter 2, replaced by quarter 3.
  5. cAlternative 2, incomplete cost collection, omitted quarter 3, replaced by quarter 4.
  6. dAlternative 3, incomplete cost collection, omitted quarters 2 and 3, replaced by quarter 4.
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BMC Health Services Research

ISSN: 1472-6963

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