Table 1 Specific guidelines for assessing and improving the methodological quality of economic evaluations of newborn screening
A. Bibliographic details | |
|---|---|
1. | Author(s) |
2. | Institutional affiliation of author(s) |
3. | Source of funding |
4. | Title |
5. | Source of publication |
6. | Publication type |
B. Study question and design | |
1. | Study question |
2. | Intervention |
3. | Control |
4. | Target population |
5. | Time horizon |
6. | Setting |
7. | Perspective |
8. | Study design |
9. | Type of economic evaluation |
10. | Study population |
11. | Primary outcome measure |
C. Modelling | |
1. | Model type |
2. | Model structure |
3. | Model assumptions |
4. | Sources used to develop and/or populate the model |
5. | Cycle length |
6. | Health states and transition |
7. | Model validation |
D. Health outcomes | |
1. | Health outcomes measured in natural units |
a. Type of health outcome measure used in the economic evaluation | |
b. Method of measurement | |
c. Source of data | |
2. | Health outcomes adjusted by utility weights or health state preference scores |
a. Type of health outcome measure used in the economic evaluation | |
b. Method of valuation | |
c. Source of data | |
3. | Health outcomes measured in monetary units |
a. Type of health outcome measure used in the economic evaluation | |
b. Method of valuation | |
c. Source of data | |
4. | Intermediate health outcomes |
a. Type of health outcome measure used in the economic evaluation | |
b. Method of measurement | |
c. Source of data | |
5. | Non-health outcomes |
a. Type of health outcome measure used in the economic evaluation | |
b. Method of measurement | |
c. Source of data | |
E. Costs | |
1. | Patient-related costs |
a. Cost categories considered in the economic evaluation | |
b. Measurement of resource data | |
c. Valuation of resource data | |
d. Source of data | |
2. | Programme-related costs |
a. Cost categories considered in the economic evaluation | |
b. Measurement of resource data | |
c. Valuation of resource data | |
d. Source of data | |
F. Discounting | |
1. | Discount rate for costs |
2. | Discount rate for health outcomes |
3. | Justification of discount rates |
G. Presentation of results | |
1. | Absolute and incremental health outcomes per newborn |
2. | Absolute and incremental costs per newborn |
3. | ICER for the primary outcome measure |
4. | Present values and trends of costs and health outcomes at the population level |
5. | Present values and trends of costs at the population level differentiated by payer |
6. | Coverage of screening |
H. Sensitivity analyses | |
1. | Parameter uncertainty |
2. | Modelling uncertainty |
3. | Methods of sensitivity analyses |
4. | Results of sensitivity analyses |
I. Discussion | |
1. | Limitations of the study |
2. | Generalizability and transferability of the economic evaluation results |
3. | Ethical and distributional issues |
J. Conclusions | |
1. | Validity of conclusions with regard to the results of the economic evaluation |
2. | Validity of conclusions with regard to the objective of the economic evaluation |
K. Commentary | |
1. | Selection of comparators |
2. | Validity of estimate of measure of effectiveness |
3. | Validity of estimate of measure of health outcome |
4. | Validity of estimate of costs |
5. | Other issues |
6. | Implications of the economic evaluation |