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Table 4 Results of the logistic regression models on the risk of hospital/ED associated CINV events

From: Impact of 5-HT3 receptor antagonists on chemotherapy-induced nausea and vomiting: a retrospective cohort study

Parameter

Breast cancer (N = 3606)

Carboplatin-treated Lung cancer (N = 4497)

Cisplatin-treated lung cancer (N = 1154)

 

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

age

NS

NS

NS

NS

NS

NS

CCI

1.247 (1.122-1.387)

<.0001

1.042 (1.012-1.073)

0.0052

NS

NS

Gender (male as reference)

Female

NA

NA

0.817 (0.678-0.985)

0.0338

NS

NS

Days with cyclophosphamide (in breast cancer) or carboplatin or cisplatin (in lung cancer) treatment

0.719 (0.619-0.836)

<.0001

0.942 (0.915-0.969)

<.0001

NS

NS

Antiemetic regimen (older 5-HT3 RAs as reference)

Palonosetron

0.618 (0.447-0.854)

0.0035

0.712 (0.586-0.864)

0.0006

0.707 (0.514-0.972)

0.0330

  1. NA: not applicable, NS: Not significant.