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Table 1 Summary of study measures

From: Comparison of pharmacy-based measures of medication adherence

Defn start of window to first dispensing last dispensing to end of window Timing^ Description of Measure
CMA1 ignored ignored ignored (# days dispensed, excluding last) / (first to last dispensing)
CMA2 ignored counted ignored (# days dispensed, including last) / (first dispensing to end of window)
CMA3 ignored ignored ignored minimum (CMA1, 1)
CMA4 ignored counted ignored minimum (CMA2, 1)
CMA5 ignored ignored counted (# days theoretical use#) / (first to last dispensing)
CMA6 ignored counted counted (# days theoretical use#) / (first dispensing to end of window)
CMA7 counted counted counted (# days theoretical use#) / (start to end of observation window), includes in numerator meds carried into observation window
CMA8 counted counted counted (# days theoretical use#) / (lagged* start of obs’n window to end of window), numerator and denominator ignore intial lag period
  1. ^refers to whether the timing of the dispensing (actual date dispensed) is taken into account in the calculations or is ignored.
  2. #assumes medications taken as directed and new medications “banked” until needed.
  3. *lag refers to initial period covered by medication supply on hand at start of observation window. Medications dispensed during lag interval are “banked” and counted starting with end of lag.