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Table 4 Effect of demographic and clinical predictors on eventual bronchiolitis episodes >1 day in multivariate analysis

From: Frequency, duration and predictors of bronchiolitis episodes of care among infants ≥32 weeks gestation in a large integrated healthcare system: a retrospective cohort study

Clinical and demographic predictors

Beta

Odds Ratio (95% CI)

Sex (Male)

0.38

1.47 (1.40–1.54)

Racea

  White

1.00

reference

  African-American

0.01

1.01 (0.93–1.10)

  Asian

−0.17

0.85 (0.79–0.90)

  Hispanic

0.13

1.13 (1.07–1.20)

  Other/unknown

−0.11

0.89 (0.82–0.98)

Gestational age, wk

  32–33

0.58

1.79 (1.53–2.09)

  34–36

0.43

1.53 (1.41–1.66)

  37

0.18

1.20 (1.10–1.31)

  38–40

1.00

reference

  ≥41

−0.11

0.90 (0.84–0.96)

  Small for gestational ageb

0.32

1.37 (1.16–1.61)

  Congenital anomaly presentc

0.15

1.17 (1.08–1.27)

Family history of asthmad

  None

1.00

reference

  Father only

0.24

1.27 (1.08–1.50)

  Mother only

0.45

1.56 (1.41–1.72)

≥1 sibling <5 y of age in home

0.37

1.45 (1.39–1.52)

O2 exposure and BPDe

  No O2 exposure, no BPD

1.00

reference

  <200 hr O2, no BPD

0.22

1.25 (1.12–1.39)

  ≥200 hr O2, no BPD

0.88

2.41 (1.89–3.07)

  BPDf

0.69

1.99 (1.13–3.49)

Maternal age, y

  <18

0.03

1.03 (0.85–1.26)

  18–34

1.00

reference

  ≥35

−0.09

0.91 (0.86–0.96)

  1. BPD = bronchopulmonary dysplasia.
  2. aClassification of race/ethnicity in this study was based on the race of infants' mothers, as self-reported to the birth certificate clerk interviewing them at the Kaiser Permanente hospitals described in this study. Race was assessed in this study because of the well-known differences in RSV severity by race.
  3. bBased on the algorithm of Brenner WE, et al. [19].
  4. cSee text for list of included International Classification of Diseases codes.
  5. dAscertained by electronic scanning of parental records, which included encounters and diagnoses identified in the Significant Problem List by the parent’s physician.
  6. eOxygen exposure, in hours, during the birth hospitalization. See text for details.
  7. fAll infants with BPD had ≥200 hours of oxygen exposure during the neonatal period.