Table 3 Study Results
From: Does GP training in depression care affect patient outcome? - A systematic review and meta-analysis
Study | Follow Up | Attrition Rate %a | Outcome | Results | Limitations | Effect Sizeb |
|---|---|---|---|---|---|---|
Baker (2001) [36] | 16 weeks | 6 | Proportion of patients w/BDI < 11 | Sign. diff in proportion of patients w/BDI > 11 (OR = 2.5) | Tailored intervention that makes GP comparison impossible since they all received diff kinds of intervention | / |
Bosmans (2006) [33] | 12 mo | 21 | PRIME-MD | No sign. diff in MD recovery | Possible Hawthorne effect, less severe episodes of MD in primary care, no blinding of patients | -0.07 |
Gask (2004) [38] | 3, 12 mo | 37 | HAM-D | No sign. diff in scores at both follow up points | Use of a new-onset (depressed less than 6 mo) sample Attrition rate rather high | -0.24 |
Kendrick (2001) [34] | 12 mo | 19 | Hospital Admittance | No sign. difference | Implemented guidelines had been tested in highly selected samples Dimensional diagnosis Potential conservative bias (chronic depressed patients) | / |
Thompson (2000) [35] | 6 weeks/6 mo | 50 | HAD | No diff in improvement, no diff in caseness rating at both points Only patients recognized as cases at baseline improve sign. during first 6 weeks (p = 0.044), no diff at 6 mo | See Kendrick (2001) | / |
Diagnosis sensitivity | No diff in sensitivity nor specificity | See Kendrick (2001) | / | |||
King (2002) [41] | 6 mo | 10 | BDI | No sign. diff in BDI scores (p = 0.84) | Smaller sample than anticipated Cut off score for inclusion rather high (makes intervention effect of CBT by lay GPs less likely) | 0.08 |
Llewellyn-Jones (1999) [40] | 9.5 mo | 23 | GDS | Sign. change in GDS scores | Serial mono-centered design Control group assessment before implementation of intervention | -0.17 |
Rost (2001) [44] | 6 mo | 10 | mCES-D | Sign. reduction in score in patients beginning new treatment episode | GP training effect unclear, feedback of diagnosis could be responsible for treatment effect Homogenous sample | -0.29 |
Pyne (2003) [43] | 12 mo | 65 | Depression severity | Sign. decrease (7.7 units) in experimental group | See Rost (2001) | / |
Rost (2005) [45] | 24 mo | 70 | Depression Free Days | Sign. more depression free days in experimental group (647.6 vs. 558.2) | See Rost (2001) | / |
Worrall (1999) [39] | 6 mo | ? | Gain score CES-D | Sign. improvement in experimental group | Possible Hawthorne effect | -0.22 |