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Table 1 Drug groups included in the analysis, branded manufacturers between brackets and patent expiry dates

From: Analyzing generic and branded substitution patterns in the Netherlands using prescription data

Drug name

Branded drug

Patent expiry datea

ACE Inhibitors

  

   Enalapril

Renitec® [MSD]

13-12-1999

   Lisinopril

Zestril® [AstraZeneca]

8-10-2002

   Ramipril

Tritace® [Sanofi-Aventis]

13-1-2004

   Quinapril

Acupril® [Pfizer]

5-10-2004

   Fosinopril

Newace® [BMS]

4-7-2005

Antidepressants

  

   Fluoxetine

Prozac® [Eli Lilly]

14-12-1999

   Paroxetine

Seroxat® [GSK]

12-7-2001

   Citalopram

Cipramil® [Lundbeck]

1-2-2002

   Moclobemide

Aurorix® [Roche]

4-4-2002

   Mirtrazapine

Remeron® [Shering-Plough]

13-9-2004

   Sertraline

Zoloft® [Pfizer]

28-10-2005

PPIs

  

   Omperazol

Losec® [AstraZeneca]

18-4-2002

   Lansoprazol

Prezal® [Sanofi-Aventis]

19-12-2005

Statins

  

   Simvastatine

Zocor® [MSD]

1-5-2003

   Pravastatine

Selektine® [BMS]

2-8-2004

  1. a Defined as the date of the first prescription encountered in IADB.nl