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Table 1 Characteristics of cohort by presence of fixed airflow obstruction (GOLD/ATS/ERS standard)

From: The validity of using ICD-9 codes and pharmacy records to identify patients with chronic obstructive pulmonary disease

 

Cohort (n = 9573)

 
 

No fixed obstruction

Fixed obstruction

p value

Characteristic*

(FEV1/FVC > 0.70)

(FEV1/FVC ≤ 0.70)

 

Subjects, n

5009

4564

 

Male, n (%)

4567 (91)

4435 (97)

<0.001

Age, years

59 (14)

66 (11)

<0.001

Body Mass Index, n (%)

  

<0.001

   15-18.5

29 (0.6)

135 (3.0)

 

   18.5-25

714 (14)

1352 (30)

 

   25-30

1664 (33)

1654 (36)

 

   30-55

2602 (52)

1423 (31)

 

Comorbidities, n (%)

   

   Hypertension

2667 (53)

2402 (53)

0.55

   Diabetes

1174 (23)

792 (17)

<0.001

   Congestive heart failure

533 (11)

517 (11)

0.28

   Myocardial infarction

101 (2)

113 (2.5)

0.13

   Atrial fibrillation

504 (10)

496 (11)

0.20

   Depression

1176 (23)

858 (19)

<0.001

   Schizophrenia

92 (1.8)

85 (1.9)

0.93

Smoking status, n (%)

  

<0.001

   Never/Former

3616 (72)

2633 (58)

 

   Current

1393 (28)

1931 (42)

 

FEV1, L, mean (SD)

2.74 (0.81)

1.74 (0.74)

<0.001

FEV1, % predicted, mean (SD)

80 (40)

54 (19)

<0.001

Severity of airflow limitation (FEV1, % predicted), n (%)

   

   GOLD I: Mild (≥80%)

-

458 (10)

 

   GOLD II: Moderate (50%-79%)

-

2202 (48)

 

   GOLD III: Severe (30%-49%)

-

1362 (30)

 

   GOLD IV: Very severe (<30%)

-

541 (12)

 

Number of albuterol MDI, n (%)

   

   0

2925 (58)

1789 (39)

 

   1-5

1053 (21)

872 (19)

 

   6+

1031 (21)

1903 (42)

 

Number of ipratroprium MDI, n (%)

  

<0.001

   0

3936 (79)

2086 (46)

 

   1-2

159 (3)

219 (5)

 

   3+

914 (18)

2259 (50)

 
  1. *Numbers represent mean (SD) unless otherwise noted.
  2. FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; MDI, metered dose inhaler.