Skip to main content

Table 3 Study outcomes and measures

From: Protocol for implementation of family health history collection and decision support into primary care using a computerized family health history system

Variable Measure Source
Primary Effectiveness Outcomes
   Appropriate breast cancer screening Risk-based guideline screening performed Genetic counselor pedigree and chart review
   Appropriate ovarian cancer screening Risk-based guideline screening performed Genetic counselor pedigree and chart review
   Appropriate colon cancer screening Risk-based guideline screening performed Genetic counselor pedigree and chart review
   Appropriate hereditary thrombophilia testing Risk-based guideline screening performed Genetic counselor pedigree and chart review
Secondary Effectiveness Outcomes
   Patient health-related behaviors Diet
Exercise
Smoking status
Intention to obtain cancer screening
Knowledge about genetic testing
HINTS[16] given at baseline, 3 month and 12 months
   Provider care patterns Orders for:
Screening studies
Referrals to GC
Genetic testing
Documentation of:
Disease risk
MeTree recommendations
Chart review
   MeTree operating characteristics Sensitivity and specificity
Net Reclassification
Number needed to treat to identify high risk
Subgroups affected by reclassification
Pedigree review by GC
Pedigree review by PCP
   Costs Referrals, office visits, procedures, testing Chart review
Implementation Outcomes
   Patient experience Satisfaction
Preparedness
Ease of use
Level of anxiety
Time to use
Questions\resource needs
Post-MeTree survey
MeTree
Study Coordinator
   Provider experience Agreement with recommendations
Does it change practice
Recommend it to peers
Quality and usefulness of reports
Impact on patient flow
Time spent discussing MeTree reports
Provider survey and interviews
   Clinic needs Resource needs to implement
Assistance required for patients/providers
Training/time required for clinic staff
Study coordinators
Interviews
Covariates
   Demographics Age
Gender
Ethnicity
MeTree input
   Education level   Baseline survey
   Insurance   Baseline survey
   Family Size
% with cancer
MeTree input
   BMI   Measured at triage
   Clinic   
   Provider Year of medical school graduation
Gender
Provider survey
  1. GC = genetic counselor; PCP = primary care provider