Determinants of generic drug substitution in Switzerland

Decollogny, Anne; Eggli, Yves; Halfon, Patricia; Lufkin, Thomas M

doi:10.1186/1472-6963-11-17

BMC Health Services Research

Table 1 Descriptive statistics and univariate logit estimates

From: Determinants of generic drug substitution in Switzerland

	Frequency	Substitution rate	Odds ratio	95%CI
OUTCOME VARIABLE Use of a generic drug (yes = 1, no = 0)	0.313
CANTONS
Aargau (reference)	0.372	0.433
Vaud	0.329	0.350	0.706	[0.689, 0.722]
Ticino	0.299	0.124	0.186	[0.181, 0.192]
PATIENTS' VARIABLES Female:
no (reference)	0.378	0.317
yes	0.622	0.311	0.972	[0.952, 0.993]
Age:
0-19	0.100	0.411	2.057	[1.986, 2.131]
20-39	0.158	0.410	2.050	[1.989, 2.112]
40-59	0.250	0.344	1.543	[1.502, 1.585]
60-79 (reference)	0.356	0.254
80+	0.136	0.228	0.868	[0.838, 0.900]
Optional health insurance deductible:
no (reference)	0.619	0.344
yes	0.381	0.264	0.685	[0.671,. 0.700]
Out-of-pocket participation:
no (reference)	0.396	0.241
yes	0.604	0.361	1.777	[1.740, 1.816]
Treatment complexity:
1-5 drugs	0.215	0.424	1.429	[1.390, 1.469]
6-10 drugs (reference)	0.290	0.340
11-15 drugs	0.223	0.280	0.757	[0.735, 0.779]
16-20 drugs	0.139	0.246	0.634	[0.613, 0.657]
21+ drugs	0.133	0.202	0.491	[0.473, 0.509]
PHYSICIANS' VARIABLES Specialist prescriber:
no (reference)	0.777	0.314
yes	0.223	0.310	0.978	[0.955, 1.003]
Hospital prescriber:
no (reference)	0.880	0.325
yes	0.120	0.225	0.603	[0.583,.0.624]
SUBSTITUTION GROUPS' VARIABLES Number of generics
1-2 (reference)	0.333	0.153
3-4	0.260	0.374	3.322	[3.225, 3.422]
5-6	0.298	0.415	3.934	[3.823, 4.049]
7+	0.110	0.382	3.430	[3.305, 3.559]
Number of treated patients:
1-1000 (reference)	0.361	0.263
1001-2000	0.259	0.322	1.334	[1.299, 1.370]
2001-3000	0.122	0.223	0.803	[0.774, 0.834]
3001+	0.257	0.418	2.017	[1.965, 2.070]
Price of brand medication:
1st quintile	0.189	0.327	1.000	[0.969, 1.031]
2nd quintile	0.165	0.251	0.689	[0.666, 0.713]
3rd quintile (reference)	0.239	0.327
4th quintile	0.187	0.328	1.002	[0.972, 1.034]
5th quintile	0.220	0.321	0.972	[0.943,.1.001]
Relative price difference:
1st quintile	0.188	0.200	0.599	[0.578, 0.620]
2nd quintile	0.200	0.347	1.267	[1.227, 1.308]
3rd quintile (reference)	0.206	0.295
4th quintile	0.204	0.301	1.029	[0.996, 1.062]
5th quintile	0.203	0.416	1.701	[1.649, 1.754]
Administration mode:
Oral (reference)	0.839	0.328
Topic	0.095	0.285	0.817	[0.788, 0.847]
Inhalation, nasal & ophthalmic	0.032	0.046	0.099	[0.087, 0.112]
Parenteral, rectal & vaginal	0.034	0.273	0.769	[0.726, 0.815]
Original with special galenic form:
no (reference)	0.862	0.338
yes	0.138	0.160	0.373	[0.359, 0.386]
At least one drug sold under license:
no (reference)	0.818	0.316
yes	0.182	0.300	0.929	[0.904, 0.954]
Multiple package sizes:
no (reference)	0.575	0.294
yes	0.425	0.339	1.232	[1.207, 1.258]
Observations	173,212

Back to article page

ISSN: 1472-6963

Contact us

General enquiries: journalsubmissions@springernature.com