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Table 4 Cost-effectiveness of bisphosphonates for real-world and ideal persistence alternatives

From: Cost of non-persistence with oral bisphosphonates in post-menopausal osteoporosis treatment in France

Alternatives

 

No-treatment

Real-world persistence

Ideal persistence

Costs (Discounted)

Average per patients

€3,402

€3,110

€2,833

 

Incremental

--

-€293*

-€277**

Costs (Undiscounted)

Average per patients

4,428 €

€3,979

€3,529

 

Incremental

--

-€449*

-€450**

Fractured women

Proportion

0.671

0.600

0.491

 

Incremental

--

-0.071

-0.109††

ICER

Discounted

--

(Dominated)

€4,110

(Dominated)

€2,535

 

Undiscounted

--

(Dominated)

€6,310

(Dominated)

€4,114

Premature deaths

Proportion

0.061

0.049

0.034

 

Incremental

--

-0,012

-0,015††

ICER

Discounted

--

(Dominated)

€25,073

(Dominated)

€18,442

 

Undiscounted

--

(Dominated)

€38,489

(Dominated)

€29,932

  1. * μc Real-world persistence--μc No treatment; ** μc Ideal persistence--μc Real-world persistence
  2. μE Real-world persistence--μE No treatment; †† μE Ideal persistence--μE Real-world persistence