Table 5 Model comparisons for mortality and hospitalization for osteoporosis cohort, full and age-restricted
| Model | Full cohort (n = 28,068) | Age 65+ (n = 20,090) | ||||
|---|---|---|---|---|---|---|
|
c-statistic (95% CI) |
Brier score (SD) | Δ c(%) |
c-statistic (95% CI) |
Brier Score (SD) | Δ c(%) | |
| Death | ||||||
| Base model |
0.758 (0.745, 0.771) |
0.042 (0.175) | -- |
0.718 (0.703, 0.733) |
0.055 (0.196) | -- |
| + # diagnoses |
0.792
(0.780, 0.804) |
0.042 (0.171) | 0.034 (4.48) |
0.756
(0.742, 0.769) |
0.054 (0.191) | 0.038 (5.29) |
| + Charlson |
0.811
(0.800, 0.822) |
0.042 (0.170) | 0.053 (6.95) |
0.772
(0.759, 0.785) |
0.054 (0.190) | 0.054 (7.57) |
| + Elixhauser |
0.827
(0.817, 0.838) |
0.040 (0.166) | 0.069 (9.09) |
0.793
(0.780, 0.805) |
0.052 (0.185) | 0.075 (10.42) |
| + # drugs |
0.782
(0.769, 0.794) |
0.042 (0.172) | 0.024 (3.10) |
0.746
(0.732, 0.760) |
0.054 (0.191) | 0.028 (3.91) |
| + CDS |
0.778
(0.766, 0.791) |
0.042 (0.172) | 0.020 (2.62) |
0.741
(0.727, 0.754) |
0.054 (0.192) | 0.023 (3.15) |
| One or more hospitalizations | ||||||
| Base model |
0.579 (0.572, 0.586) |
0.220 (0.157) | -- |
0.550 (0.542, 0.558) |
0.232 (0.129) | -- |
| + # diagnoses |
0.667
(0.660, 0.673) |
0.208 (0.178) | 0.088 (15.14) |
0.647
(0.639, 0.654) |
0.220 (0.157) | 0.097 (17.54) |
| + Charlson |
0.619
(0.612, 0.626) |
0.216 (0.166) | 0.040 (6.98) |
0.598
(0.590, 0.606) |
0.227 (0.141) | 0.048 (8.73) |
| + Elixhauser |
0.637
(0.630, 0.644) |
0.212 (0.173) | 0.058 (10.08) |
0.620
(0.612, 0.628) |
0.223 (0.151) | 0.070 (12.65) |
| + # drugs |
0.631
(0.624, 0.638) |
0.213 (0.168) | 0.052 (9.02) |
0.609
(0.601, 0.618) |
0.225 (0.144) | 0.059 (10.80) |
| + CDS |
0.618
(0.611, 0.625) |
0.215 (0.166) | 0.039 (6.69) |
0.597
(0.589, 0.605) |
0.227 (0.141) | 0.047 (8.61) |
| Two or more hospitalizations | ||||||
| Base model |
0.606 (0.597, 0.615) |
0.124 (0.243) | -- |
0.570 (0.559, 0.580) |
0.139 (0.245) | -- |
| + # diagnoses |
0.697
(0.688, 0.705) |
0.118 (0.235) | 0.090 (14.92) |
0.669
(0.659, 0.679) |
0.133 (0.238) | 0.099 (17.37) |
| + Charlson |
0.650
(0.641, 0.659) |
0.122 (0.240) | 0.044 (7.19) |
0.619
(0.609, 0.630) |
0.137 (0.242) | 0.050 (8.73) |
| + Elixhauser |
0.672
(0.663, 0.681) |
0.119 (0.237) | 0.066 (10.86) |
0.645
(0.634, 0.655) |
0.135 (0.239) | 0.075 (13.15) |
| + # drugs |
0.656
(0.647, 0.665) |
0.121 (0.237) | 0.050 (8.28) |
0.625
(0.615, 0.636) |
0.136 (0.240) | 0.056 (9.80) |
| + CDS |
0.651
(0.642, 0.660) |
0.121 (0.238) | 0.045 (7.41) |
0.620
(0.610, 0.631) |
0.137 (0.240) | 0.051 (8.89) |
