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Table 4 Model comparisons for mortality and hospitalization for diabetes cohort, full and age-restricted

From: Comparing comorbidity measures for predicting mortality and hospitalization in three population-based cohorts

Model Full cohort (n = 41,925) Age 65+ (n = 20,025)
  c-statistic
(95% CI)
Brier
score (SD)
Δ c(%) c-statistic
(95% CI)
Brier
score (SD)
Δ c(%)
Death
Base model 0.781
(0.770, 0.791)
0.038
(0.166)
-- 0.695
(0.680, 0.709)
0.067
(0.209)
--
+ # diagnoses 0.818
(0.809, 0.828)
0.037
(0.161)
0.037 (4.78) 0.749
(0.736, 0.762)
0.065
(0.202)
0.054 (7.81)
+ Charlson 0.830
(0.821, 0.839)
0.037
(0.161)
0.049 (6.33) 0.764
(0.752, 0.776)
0.065
(0.202)
0.070 (10.02)
+ Elixhauser 0.845
(0.836, 0.854)
0.036
(0.156)
0.064 (8.20) 0.788
(0.776, 0.800)
0.063
(0.196)
0.094 (13.50)
+ # drugs 0.799
(0.789, 0.810)
0.038
(0.163)
0.018 (2.36) 0.729
(0.715, 0.742)
0.065
(0.204)
0.034 (4.92)
+ CDS 0.789
(0.779, 0.800)
0.038
(0.165)
0.009 (1.11) 0.709
(0.695, 0.723)
0.066
(0.207)
0.014 (2.07)
One or more hospitalizations
Base model 0.610
(0.604, 0.616)
0.211
(0.174)
-- 0.547
(0.539, 0.556)
0.238
(0.104)
--
+ # diagnoses 0.701
(0.695, 0.706)
0.195
(0.194)
0.091 (14.90) 0.655
(0.647, 0.663)
0.224
(0.148)
0.108 (19.63)
+ Charlson 0.666
(0.660, 0.672)
0.203
(0.187)
0.056 (9.21) 0.621
(0.613, 0.629)
0.231
(0.130)
0.074 (13.45)
+ Elixhauser 0.677
(0.671, 0.682)
0.198
(0.192)
0.067 (10.98) 0.634
(0.626, 0.642)
0.226
(0.143)
0.086 (15.76)
+ # drugs 0.641
(0.635, 0.647)
0.206
(0.181)
0.031 (5.11) 0.604
(0.596, 0.612)
0.232
(0.125)
0.056 (10.28)
+ CDS 0.624
(0.618, 0.630)
0.208
(0.177)
0.014 (2.31) 0.578
(0.570, 0.587)
0.235
(0.115)
0.031 (5.65)
Two or more hospitalizations
Base model 0.617
(0.609, 0.625)
0.113
(0.242)
-- 0.546
(0.535, 0.556)
0.146
(0.245)
--
+ # diagnoses 0.726
(0.719, 0.733)
0.106
(0.230)
0.109 (17.61) 0.674
(0.665, 0.684)
0.139
(0.237)
0.129 (23.55)
+ Charlson 0.694
(0.687, 0.702)
0.110
(0.236)
0.077 (12.55) 0.643
(0.633, 0.653)
0.143
(0.240)
0.097 (17.76)
+ Elixhauser 0.709
(0.702, 0.717)
0.107
(0.232)
0.092 (14.96) 0.655
(0.645, 0.665)
0.139
(0.237)
0.109 (20.02)
+ # drugs 0.651
(0.643, 0.658)
0.111
(0.237)
0.034 (5.45) 0.603
(0.592, 0.614)
0.144
(0.241)
0.057 (10.49)
+ CDS 0.633
(0.625, 0.641)
0.112
(0.240)
0.016 (2.63) 0.580 (0.569, 0.590) 0.145
(0.242)
0.034 (6.22)
  1. Base model includes age, age2, sex, income quintile, and geography
  2. CDS = Chronic Disease Score
  3. Δc = difference in the c-statistic between the base and full models; c-statistics in boldface font are significantly different from the c-statistic for the base model, according to the method of DeLong et al. [39]
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