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Table 4 Side-effect profiles of intravenous immunoglobulin infusion and therapeutic plasma exchange

From: Cost-minimization analysis of the direct costs of TPE and IVIg in the treatment of Guillain-Barré syndrome

Intravenous Immunoglobulin Infusion [2528] Therapeutic Plasma Exchange [2123]
Mild (common) Mild (common)
Fever Fever
Facial flushing Paresthesias due to hypocalcemia
Malaise Hematoma at site of vascular access
Headache Bleeding at site of vascular access
Chills Muscle cramping due to hypocalcemia
Myalgia Nausea
Fatigue Vomiting
Dyspnea Pallor
Back Pain Diaphoresis
Abdominal pain Hypotension
Nausea Tachycardia
Vomiting Urticaria
Diarrhea Pruritis
Hypotension Hypofibrinogenemia
Severe (uncommon) Severe (uncommon)
Anaphylaxis Anaphylaxis
Acute renal failure Air embolism
Thromboembolic events Arrhythmia
   Stroke Hemolysis
   Myocardial infarction Thrombocytopenia
   Deep venous thrombosis Transfusion Related Acute Lung Injury
Aseptic meningitis Pneumothorax due to central line
Progressive neurodegeneration Hemothorax due to central line
Serum sickness Tetany
Transfusion Related Acute Lung Injury  
Leukocytoclastic vasculitis  
Erythema multiforme