|
Variable
|
First 250 patients
|
Last 250 patients
|
Change
|
p-value
|
|---|
|
Patient characteristics
| | | | |
|---|
|
Mean age, in years (SD)
|
62.6 (18.0)
|
59.5 (19.1)
| |
0.057
|
|
Gender, number of females
|
147 (58.8)
|
151 (60.4)
| |
0.715
|
|
Indications
| | | | |
|
Cardiac murmur only
|
79 (31.6)
|
100 (40.0)
|
+
|
0.050
|
|
Any dyspnoea
|
111 (44.4)
|
65 (26.0)
|
-
|
0.000
|
|
Dyspnoea only
|
50 (20.0)
|
20 (8.0)
|
-
|
0.000
|
|
Dyspnoea and peripheral oedema
|
24 (9.6)
|
11 (4.4)
|
-
|
0.023
|
|
'Other' indications
|
41 (16.4)
|
67 (26.8)
|
+
|
0.005
|
|
'Other' only
|
27 (10.8)
|
55 (22.0)
|
+
|
0.001
|
|
Echocardiographic outcome
| | | | |
|
Any LVD
|
110 (44.0)
|
85 (34.0)
|
-
|
0.022
|
|
Diastolic LVD only
|
95 (38.0)
|
74 (29.6)
|
-
|
0.047
|
|
Any valve disease
|
65 (26.0)
|
43 (17.2)
|
-
|
0.017
|
|
Mitral insufficiency
|
18 (7.2)
|
8 (3.2)
|
-
|
0.044
|
|
Pulmonary insufficiency
|
7 (2.8)
|
0 (0)
|
-
|
0.008
|
|
Tricuspid insufficiency
|
21 (8.4)
|
3 (1.2)
|
-
|
0.000
|
|
LVH
|
121 (48.4)
|
99 (39.6)
|
-
|
0.047
|
|
PHT
|
48 (19.2)
|
23 (9.2)
|
-
|
0.001
|
|
No disease*
|
55 (22.0)
|
82 (32.8)
|
+
|
0.007
|
|
Outcome per indication
| | | | |
|
PHT/cardiac murmur
|
24/131 (18.3)
|
11/147 (7.5)
|
-
|
0.007
|
|
PHT/dyspnoea
|
23/111 (20.7)
|
6/65 (9.2)
|
-
|
0.047
|
|
No disease/dyspnoea
|
23/111 (20.7)
|
23/65 (35.4)
|
+
|
0.033
|
|
No disease/'other'
|
6/41 (14.6)
|
22/67 (32.8)
|
+
|
0.036
|
|
Cardiologist's advice in patients with positive echocardiographic outcome
| | | | |
|
Any advice
|
78/195 (40.0)
|
100/168 (59.5)
|
+
|
0.000
|
|
Repeat echocardiogram in x years
|
8/195 (4.1)
|
28/168 (16.7)
|
+
|
0.000
|
|
Adjust medication
|
8/195 (4.1)
|
21/168 (12.5)
|
+
|
0.003
|
- Abbreviations: LVD left ventricular dysfunction; LVH left ventricular hypertrophy, PHT pulmonary hypertension; + increase; - decrease
- *No disease: neither valve disease nor left ventricular dysfunction or left ventricular hypertrophy or pulmonary hypertension or septum defects
