|  | Estimation (n = 476 558) 60% | Validation (n = 316 681) 40% | p-value | ||
---|---|---|---|---|---|---|
Rx-MG label | Description | (n)a | (%) | (n)a | (%) | Â |
 | Allergy/immunology |  |  |  |  |  |
ALLx010 |    Acute minor | 252 733 | 53.00% | 168 474 | 53.20% | 0.145 |
ALLx030 |    Chronic inflammatory | 86 509 | 18.20% | 57 687 | 18.20% | 0.474 |
ALLx040 |    Immune disorders | 28 | < 0.1% | 18 | < 0.1% | 0.913 |
ALLx050 |    Transplant | 437 | 0.10% | 277 | 0.10% | 0.538 |
 | Cardiovascular |  |  |  |  |  |
CARx010 |    Chronic medical | 17 517 | 3.70% | 11 817 | 3.70% | 0.197 |
CARx020 |    Congestive heart failure | 14 754 | 3.10% | 9 956 | 3.10% | 0.229 |
CARx030 |    High blood pressure | 79 187 | 16.60% | 52 759 | 16.70% | 0.610 |
CARx040 |    Hyperlipidemia | 21 877 | 4.60% | 14 572 | 4.60% | 0.821 |
CARx050 |    Vascular disorders | 57 775 | 12.10% | 38 503 | 12.20% | 0.641 |
 | Ears-nose-throat |  |  |  |  |  |
EARx010 |    Acute minor | 3 653 | 0.80% | 2 424 | 0.80% | 0.956 |
 | Endocrine |  |  |  |  |  |
ENDx010 |    Bone disorders | 2 088 | 0.40% | 1 492 | 0.50% | 0.032 |
ENDx020 |    Chronic medical | 17 059 | 3.60% | 11 413 | 3.60% | 0.569 |
ENDx030 |    Diabetes with insulin | 4 813 | 1.00% | 3 167 | 1.00% | 0.666 |
ENDx040 |    Diabetes without insulin | 21 991 | 4.60% | 14 634 | 4.60% | 0.892 |
ENDx050 |    Thyroid disorders | 4 050 | 0.80% | 2 681 | 0.80% | 0.877 |
 | Eye |  |  |  |  |  |
EYEx010 |    Acute minor: curative | 103 889 | 21.80% | 69 173 | 21.80% | 0.648 |
EYEx020 |    Acute minor: palliative | 79 750 | 16.70% | 52 753 | 16.70% | 0.371 |
EYEx030 |    Glaucoma | 31 213 | 6.50% | 20 959 | 6.60% | 0.227 |
 | Female reproductive |  |  |  |  |  |
FREx010 |    Hormone regulation | 16 101 | 3.40% | 10 643 | 3.40% | 0.667 |
FREx020 |    Infertility | 2 772 | 0.60% | 1 826 | 0.60% | 0.771 |
FREx030 |    Pregnancy and delivery | 10 894 | 2.30% | 7 113 | 2.20% | 0.243 |
 | Gastrointestinal/hepatic |  |  |  |  |  |
GASx010 |    Acute minor | 288 597 | 60.60% | 191 999 | 60.60% | 0.533 |
GASx020 |    Chronic liver disease | 11 622 | 2.40% | 7 708 | 2.40% | 0.893 |
GASx030 |    Chronic stable | 140 349 | 29.50% | 93 089 | 29.40% | 0.596 |
GASx040 |    Inflammatory bowel disease | 918 | 0.20% | 613 | 0.20% | 0.926 |
GASx050 |    Pancreatic disorder | 33 833 | 7.10% | 22 647 | 7.20% | 0.379 |
GASx060 |    Peptic disease | 91 510 | 19.20% | 61 344 | 19.40% | 0.062 |
 | General signs and symptoms |  |  |  |  |  |
GSIx010 |    Nausea and vomiting | 69 209 | 14.50% | 46 281 | 14.60% | 0.257 |
GSIx020 |    Pain | 108 551 | 22.80% | 72 225 | 22.80% | 0.765 |
GSIx030 |    Pain and inflammation | 371 310 | 77.90% | 247 044 | 78.00% | 0.316 |
 | Genitourinary |  |  |  |  |  |
GURx010 |    Acute minor | 27 817 | 5.80% | 18 636 | 5.90% | 0.375 |
GURx020 |    Chronic renal failure | 1 086 | 0.20% | 666 | 0.20% | 0.102 |
 | Hematologic |  |  |  |  |  |
HEMx010 |    Coagulation disorders | 35 047 | 7.40% | 23 460 | 7.40% | 0.369 |
 | Infections |  |  |  |  |  |
INFx010 |    Acute major | 26 329 | 5.50% | 17 191 | 5.40% | 0.065 |
INFx020 |    Acute minor | 250 114 | 52.50% | 165 757 | 52.30% | 0.217 |
INFx030 |    HIV/AIDS | 308 | 0.10% | 203 | 0.10% | 0.928 |
INFx040 |    Tuberculosis | 1 350 | 0.30% | 883 | 0.30% | 0.714 |
 | Malignancies |  |  |  |  |  |
MALx010 |    Malignancies | 3 176 | 0.70% | 2 074 | 0.70% | 0.535 |
 | Musculoskeletal |  |  |  |  |  |
MUSx010 |    Gout | 17 046 | 3.60% | 11 181 | 3.50% | 0.277 |
MUSx020 |    Inflammatory conditions | 515 | 0.10% | 342 | 0.10% | 0.992 |
 | Neurologic |  |  |  |  |  |
NURx010 |    Alzheimer's disease | 194 | < 0.1% | 147 | < 0.1% | 0.230 |
NURx020 |    Chronic medical | 56 048 | 11.80% | 37 471 | 11.80% | 0.334 |
NURx030 |    Migraine headache | 5 341 | 1.10% | 3 588 | 1.10% | 0.612 |
NURx040 |    Parkinson's disease | 11 633 | 2.40% | 7 656 | 2.40% | 0.506 |
NURx050 |    Seizure disorder | 8 760 | 1.80% | 5 846 | 1.80% | 0.799 |
 | Psychosocial |  |  |  |  |  |
PSYx010 |    Attention-deficit disorder | 692 | 0.10% | 465 | 0.10% | 0.852 |
PSYx020 |    Addiction | 2 531 | 0.50% | 1 614 | 0.50% | 0.195 |
PSYx030 |    Anxiety | 91 748 | 19.30% | 61 452 | 19.40% | 0.091 |
PSYx040 |    Depression | 19 482 | 4.10% | 12 951 | 4.10% | 0.973 |
PSYx050 |    Acute minor | 32 618 | 6.80% | 21 680 | 6.80% | 0.979 |
PSYx060 |    Chronic unstable | 29 899 | 6.30% | 20 190 | 6.40% | 0.069 |
 | Respiratory |  |  |  |  |  |
RESx010 |    Acute minor | 301 188 | 63.20% | 200 630 | 63.40% | 0.166 |
RESx020 |    Chronic medical | 29 992 | 6.30% | 19 890 | 6.30% | 0.820 |
RESx030 |    Cystic fibrosis | 77 | < 0.1% | 47 | < 0.1% | 0.646 |
RESx040 |    Airway hyper-reactivity | 164 532 | 34.50% | 109 696 | 34.60% | 0.295 |
 | Skin |  |  |  |  |  |
SKNx010 |    Acne | 23 862 | 5.00% | 15 892 | 5.00% | 0.824 |
SKNx020 |    Acute and recurrent | 179 162 | 37.60% | 119 167 | 37.60% | 0.753 |
SKNx030 |    Chronic medical | 3 276 | 0.70% | 2 100 | 0.70% | 0.196 |
 | Toxic effects/adverse effects |  |  |  |  |  |
TOXx010 |    Acute major | 574 | 0.10% | 381 | 0.10% | 0.986 |
ZZZx000 |    Other and nonspecific medications | 157 388 | 33.00% | 104 784 | 33.10% | 0.564 |