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Table 3 Side effects most frequently reported by DMPA and NET-EN users

From: Counting the costs: Comparing depot medroxyprogesterone acetate and norethisterone oenanthate utilisation patterns in South Africa

Side Effect DMPA (%) NET-EN (%) P Value*
  (n = 84) (n = 95)  
Menstrual irregularities    
Amenorrhoea # 67.5 58.9 0.240
Spotting 9.5 12.6 0.510
Heavy periods 8.3 7.4 0.792
Irregular periods 3.6 10.5 0.074
Longer periods 2.4 4.2 0.497
Dysmenorrhoea 1.2 1.1 0.930
Vaginal wetness 22.6 14.7 0.175
Weight gain 14.3 8.4 0.214
Loss of libido 10.7 8.4 0.601
Dizziness 10.7 6.3 0.289
Headache 10.7 4.2 0.094
Nausea 9.5 3.2 0.077
Vaginal discharge 8.3 3.2 0.132
Vaginal discharge with odour 7.1 3.2 0.223
  1. # Includes thirty breastfeeding women. Although amenorrhoea was reported as a side effect of IPC use, it could have been lactational amenorrhoea * Chi-square (1 degree of freedom, significance tested at the 5% level)