Key input parameter | Sensitivity analyses |
---|---|
Time horizon | Five, 15, 20 years |
Discount rate | 3 %, 4 %, 6 % to future costs and effects |
Health utilities | Varied according to the upper and lower limits of the 95 % CI surrounding mean values reported by Clarke and colleagues (Clarke et al., 2002) |
Cost of complications | Varied according to the upper and lower limits of the 95 % CI surrounding mean values reported by Clarke and colleagues (Clarke et al., 2008) |
Cost in the absence of complications | Varied according to the upper and lower limits of the 95 % CI surrounding mean values reported in DTCS. |
HbA1C | Assumed that HbA1C at 6 months in the DTCS was maintained for one, two and five simulation years. |
Stroke | Assumed that no participants had a past history of stroke. |