Table 3 Alteration of disease parameters after 6 and 12 months of treatment in the entire study population and stratified by diagnosis

All patients

(n = 237)

(n = 154)

 SBP (mmHg) ± SD

148.5 ± 28.3

139.4 ± 25.4 (Δ -9.1)

<0.001 (141.5-146.4)

150.4 ± 30.3

141.5 ± 25.5 (Δ -8.9)

0.003 (142.7-149.1)

 DBP (mmHg) ± SD

88.0 ± 15.4

82.9 ± 15.3 (Δ -5.1)

0.002 (84.0-86.8)

89.3 ± 16.4

83.2 ± 13.7 (Δ -6.1)

<0.001 (84.5-87.9)

 RBG (mmol/L) ± SD

11.3 ± 6.7

11.3 ± 8.8 (Δ -0.0)

0.5308 (10.5-12.1)

10.7 ± 6.1

11.8 ± 6.8 (Δ +1.1)

0.909 (10.4-12.1)

Hypertension only

(n = 65)

(n = 33)

 SBP (mmHg) ± SD

158.2 ± 26.0

136.2 ± 25.9 (Δ -22.0)

<0.001 (142.5-152.2)

160.7 ± 32.1

139.3 ± 27.4 (Δ -21.4)

0.003 (142.5-158.1)

 DBP (mmHg) ± SD

94.8 ± 15.1

82.9 ± 15.4 (Δ -11.9)

<0.001 (86.1-91.7)

96.9 ± 19.6

84.1 ± 13.9 (Δ -12.8)

0.002 (86.2-95.1)

 RBG (mmol/L) ± SD

6.5 ± 3.3

7.1 ± 4.5 (Δ +0.6)

0.738 (5.7-7.8)

8.4 ± 5.2

10.5 ± 6.9 (Δ +2.1)

0.789 (6.8-11.9)

Diabetes only

(n = 69)

(n = 40)

 SBP (mmHg) ± SD

139.9 ± 30.6

136.0 ± 20.6 (Δ -3.9)

0.192 (133.6-142.4)

140.1 ± 33.7

132.5 ± 23.9 (Δ -7.6)

0.132 (129.6-142.9)

 DBP (mmHg) ± SD

85.5 ± 15.1

82.9 ± 16.6 (Δ -2.6)

0.171 (81.5-86.9)

87.8 ± 15.7

82.5 ± 13.1 (Δ -5.3)

0.058 (81-7-88.4)

 RBG (mmol/L) ± SD

12.6 ± 7.7

11.5 ± 6.4 (Δ -1.1)

0.203 (10.7-13.3)

10.2 ± 6.5

11.5 ± 7.3 (Δ +1.3)

0.774 (9.2-12.6)

Hypertension & diabetes

(n = 100)

(n = 80)

 SBP (mmHg) ± SD

147.7 ± 26.7

143.9 ± 27.8 (Δ -3.8)

0.161 (142.0-149.6)

152.3 ± 26.7

146.7 ± 25.1 (Δ -5.6)

0.092 (145.3-153.6)

 DBP (mmHg) ± SD

85.2 ± 14.6

83.4 ± 14.2 (Δ -1.8)

0.180 (82.3-86.3)

87.3 ± 14.6

83.1 ± 12.7 (Δ -4.2)

0.028 (83.0-87.4)

 RBG (mmol/L) ± SD

11.9 ± 6.2

12.1 ± 10.6 (Δ +0.2)

0.558 (10.7-13.3)

11.6 ± 6.1

12.4 ± 6.8 (Δ +0.8)

0.750 (10.9-13.1)